1112988-63-2Relevant academic research and scientific papers
Chiral Bis(imidazolidine)iodobenzene (I-Bidine) Organocatalyst for Thiochromane Synthesis Using an Asymmetric Michael/Henry Reaction
Arai, Takayoshi,Suzuki, Takumi,Inoue, Takahiro,Kuwano, Satoru
supporting information, p. 122 - 127 (2016/12/26)
Bis(imidazolidine)iodobenzene (I-Bidine) was designed as an organocatalyst based on previously reported imidazolidine- or oxazolidine-containing chiral metal catalysts. I-Bidine showed catalytic activity for the Michael/Henry reaction of thiosalicyl aldeh
Diversity-oriented asymmetric catalysis (DOAC): Stereochemically divergent synthesis of thiochromanes using an imidazoline-aminophenol-nickel-catalyzed michael/henry reaction
Arai, Takayoshi,Yamamoto, Yushi
supporting information, p. 1700 - 1703 (2014/04/17)
The (S,S)-diphenylethylenediamine-derived imidazoline-aminophenol-Ni complex catalyzed tandem asymmetric Michael/Henry reaction of 2-mercaptobenzaldehydes with β-nitrostyrenes to give the corresponding (2S,3R,4R)-2-aryl-3-nitrothiochroman-4-ols in up to 9
Synthesis of 2,3,4-trisubstituted thiochromanes using an organocatalytic enantioselective tandem michael-henry reaction
Dodda, Rajasekhar,Goldman, Joshua J.,Mandal, Tanmay,Zhao, Cong-Gui,Broker, Grant A.,Tiekink, Edward R. T.
body text, p. 537 - 541 (2009/05/07)
Enantioenriched 2,3,4-trisubstituted thiochromanes have been synthesized by using a cupreine-catalyzed tandem Michael addition-Henry reaction between 2-mercaptobenzaldehydes and β-nitrostyrenes. Good diastereoselectivities and enantioselectivities were obtained for the title compounds, which may be further improved through a single recrystallization (up to 98% de and > 99% ee).
