111394-44-6

Basic information

• Product Name: (Z)-2-Methoxy-5-(2-(7-Methoxy-Benzo[D][1,3]Dioxol-5-Yl)Vinyl)Phenol
• Synonyms: (Z)-2-Methoxy-5-(2-(7-Methoxy-Benzo[D][1,3]Dioxol-5-Yl)Vinyl)Phenol;combretastatin A-2;2-Methoxy-5-[(Z)-2-(7-methoxy-1,3-benzodioxol-5-yl)ethenyl]phenol
• CAS NO: 111394-44-6
• Molecular Formula: C₁₇H₁₆O₅
• Molecular Weight: 300.30594
• Mol File: 111394-44-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 483.8 °C at 760 mmHg
• Flash Point: 246.4 °C
• Appearance: /
• Density: 1.304 g/cm³
• Vapor Pressure: 5.51E-10mmHg at 25°C
• Refractive Index: 1.66
• PKA: 9.66±0.10(Predicted)
• CAS DataBase Reference: (Z)-2-Methoxy-5-(2-(7-Methoxy-Benzo[D][1,3]Dioxol-5-Yl)Vinyl)Phenol(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-2-Methoxy-5-(2-(7-Methoxy-Benzo[D][1,3]Dioxol-5-Yl)Vinyl)Phenol(111394-44-6)
• EPA Substance Registry System: (Z)-2-Methoxy-5-(2-(7-Methoxy-Benzo[D][1,3]Dioxol-5-Yl)Vinyl)Phenol(111394-44-6)

Safety Data

• Hazardous Substances Data: 111394-44-6(Hazardous Substances Data)

Usage

General Description

(Z)-2-Methoxy-5-(2-(7-Methoxy-Benzo[D][1,3]Dioxol-5-Yl)Vinyl)Phenol, also known as Gnetol, is a natural phenolic compound found in the plant Gnetum Gnemon. It is a phytoestrogen that has been studied for its potential health benefits, including its anti-inflammatory, antioxidant, and estrogenic properties. Gnetol has been shown to inhibit the growth of cancer cells and has potential applications in cancer therapy. Additionally, it has shown promise in the treatment of cardiovascular diseases and osteoporosis. Gnetol's unique chemical structure and biological activities make it an interesting compound for further research and potential pharmaceutical development.

InChI:InChI=1/C17H16O5/c1-19-14-6-5-11(7-13(14)18)3-4-12-8-15(20-2)17-16(9-12)21-10-22-17/h3-9,18H,10H2,1-2H3/b4-3+

Upstream product

• 5780-07-4 3-methoxy-4,5-methylenedioxybenzaldehyde 
• 111394-52-6 3-hydroxy-4-methoxybenzyltriphenylphosphonium bromide 
• 121042-94-2 <3-<(tert-butyldimethylsilyl)oxy>-4-methoxybenzyl>triphenylphosphonium bromide 
• 607-91-0 myristicin 
• 487-62-7 isomyristicin 
• 512184-74-6 3,4'-dimethoxy-4,5-methylenedioxy-3'-O-t-butyldimethylsilylstilbene 
• 22934-59-4 (7-methoxybenzo[d][1,3]dioxol-5-yl)methanol 
• 111394-51-5 3-hydroxy-4-methoxybenzyl bromide 
• 3934-86-9 methyl 3,4-dihydroxy-5-methoxybenzoate 
• 22934-58-3 methyl 7-methoxybenzo[d][1,3]dioxole-5-carboxylate 
• 99-24-1 methyl galloate 
• 4383-06-6 3-hydroxy-4-methoxybenzyl alcohol 
• 111394-53-7 3'-hydroxy-3,4-methylenedioxy-4',5-dimethoxy-(E)-stilbene 

Downstream Products

• 111394-49-1 combretastatin B-1 
• 111394-50-4 combretastatin A-2 3'-O-p-bromophenylcarbamate 
• 111394-47-9 combretastatin A-2 acetate 

Relevant articles and documents

Synthesis of antimitotic polyalkoxyphenyl derivatives of combretastatin using plant allylpolyalkoxybenzenes (1)

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