111411-65-5

Basic information

• Product Name: C₁₈H₁₅N₃O₄
• Synonyms: C₁₈H₁₅N₃O₄
• CAS NO: 111411-65-5
• Molecular Weight: 337.335
• Mol File: 111411-65-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₈H₁₅N₃O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₁₅N₃O₄(111411-65-5)
• EPA Substance Registry System: C₁₈H₁₅N₃O₄(111411-65-5)

Safety Data

• Hazardous Substances Data: 111411-65-5(Hazardous Substances Data)

Upstream product

• 40868-97-1 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetohydrazide 
• 123-11-5 4-methoxy-benzaldehyde 
• 4702-13-0 N-phthaloylglycine 
• 85-44-9 phthalic anhydride 
• 58455-49-5 (1,3-dioxo-1,3-dihydro-isoindol-2-yl)-acetic acid phenyl ester 
• 6780-38-7 N-phthaloylglycine chloride 

Downstream Products

• 1345842-35-4 2-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-N-[2-(4-methoxyphenyl)-4-oxothiazolidin-3-yl]acetamide 

Relevant articles and documents

Design and synthesis of 2-(1, 3-dioxoisoindolin-2-yl)-N-(4-oxo-2- substitutedthiazolidin-3-yl) acetamide derivatives as potential anticonvulsant agents

A series of 2-(1,3-dioxoisoindolin-2-yl)-N-(4-oxo-2-substitutedthiazolidin- 3-yl) acetamide derivatives were designed and synthesized using appropriate synthetic route, keeping in view the structural requirement of pharmacophore and evaluated for anticonvulsant activity and CNS depressant activities in mice. The synthesized derivatives were examined in the maximal electroshock seizure (MES), subcutaneous pentylenetetrazole (sc-PTZ) induced seizure and neurotoxicity screens and were also evaluated for behavioral activity. All the tested compounds showed protection against MES test indicative of their ability to inhibit the seizure spread.