111426-92-7Relevant academic research and scientific papers
Synthesis and biological evaluation of novel m-carborane-containing estrogen receptor partial agonists as SERM candidates
Ohta, Kiminori,Ogawa, Takumi,Kaise, Asako,Endo, Yasuyuki
, p. 3213 - 3216 (2015)
Abstract We designed and synthesized novel m-carborane-containing selective estrogen receptor modulator (SERM) candidates using previously reported m-carborane-containing ER partial agonist 1 as the lead compound. Biological activities were evaluated by m
Synthesis and biological evaluation of meta-carborane-containing phenoxyacetanilides as inhibitors of hypoxia-inducible factor (HIF)-1 transcriptional activity
Li, Guangzhe,Azuma, Soyoko,Minegishi, Hidemitsu,Nakamura, Hiroyuki
, p. 189 - 195 (2015/12/18)
meta-Carboranylphenoxyacetanilides were synthesized by copper catalyzed coupling reaction of meta-carborane and phenyl iodides. The synthesized compounds were evaluated for their ability to inhibit hypoxia-induced HIF-1 transcriptional activity using a ce
