111437-56-0

Upstream product

• 1145-80-8 N-(benzyloxycarbonyl)-L-serine 
• 106-95-6 allyl bromide 
• 74-88-4 methyl iodide 
• 51479-73-3 allyl trichloroacetimidate 
• 1676-81-9 N-benzyloxycarbonyl-L-serine methyl ester 

Downstream Products

• 111437-55-9 <3R-<3R*,6S*,7(S*)>>-N-amino>-1-oxo-3-phenylpropyl>-6-methyl-5-oxo-1-oxa-4,7-diazacyclotetradec-3-yl>methyl>-L-valyl>-L-isoleucyl>-L-histidine methyl ester 
• 111437-54-8 <3R-<3R*,6S*,7(S*)>>-N-amino>-1-oxo-3-phenylpropyl>-6-methyl-5-oxo-1-oxa-4,7-diazacyclododec-3-yl>methyl>-L-valyl>-L-isoleucyl>-L-histidine methyl ester 
• 106975-94-4 <3R-<3R*,6S*,7(S*)>>-N-amino>-1-oxo-3-phenylpropyl>octahydro-6-methyl-5-oxo-2H-1,4,7-oxadiazecin-3-yl>methyl>-L-valyl>-L-isoleucyl>-L-histidine methyl ester 
• 111437-63-9 pentafluorophenyl 2(S)-methyl-9(S)-<(benzyloxycarbonyl)amino>-3-(tert-butyloxycarbonyl)-3-aza-7,11,13-trioxatetradecanoate 
• 111437-67-3 <3R-<3R*,6S*,7(S*)>>-N-<<7-<2-<<(1,1-dimethylethoxy)carbonyl>amino>-1-oxo-3-phenylpropyl>octahydro-6-methyl-5-oxo-2H-1,4,7-oxadiazecin-3-yl>methyl>-L-valine phenylmethyl ester 
• 111437-76-4 (S)-2-{[(3R,6S)-7-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionyl)-6-methyl-5-oxo-[1,4,7]oxadiazecan-3-ylmethyl]-amino}-3-methyl-butyric acid 
• 111437-62-8 methyl 2(S)-methyl-9(S)-<(benzyloxycarbonyl)amino>-3-(tert-butyloxycarbonyl)-3-aza-7,11,13-trioxatetradecanoate 

Relevant academic research and scientific papers

Renin Inhibitors. Design and Synthesis of a New Class of Conformationally Restricted Analogues of Angiotensinogen

Molecular modeling methods have been used to design a novel series of conformationally constrained cyclic peptide inhibitors of human renin.Three goals were defined: enhanced inhibitory potency, high specificity for renin, and increased metabolic stabilit

MERCAPTOACETYLAMIDE BICYCLIC LACTAM DERIVATIVES USEFUL AS INHIBITORS OF ENKEPHALINASE AND ACE

The present invention relates to certain novel mercaptoacetylamide bicyclic lactam derivatives useful as inhibitors of enkephalinase and of ACE.These mercaptoacetylamide bicyclic lactam derivatives can be described by the following formula: STR1 whe