1114370-90-9Relevant academic research and scientific papers
Novel synthesis of 1,3,5-trisubstituted 2-pyrazolines promoted by chlorotrimethylsilane
Xie, Zengyang,Bian, Xiaoqin,Geng, Xin,Li, Shuangshuang,Wang, Cunde
, p. 52 - 54 (2008)
1,3,5-Trisubstituted-2-pyrazolines were effectively synthesised by utilising chlorotrimethylsilane as an efficient promoter in the cyclisation addition of Phenylhydrazine to chalcones under nitrogen in acetonitrile. The clean, mild reaction conditions, high yields and a simple workup of target compounds were attractive features of the reaction which enables a facile preparative procedure for building the pyrazoline ring.
