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1114394-52-3

1114394-52-3

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1114394-52-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1114394-52-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,1,4,3,9 and 4 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1114394-52:
(9*1)+(8*1)+(7*1)+(6*4)+(5*3)+(4*9)+(3*4)+(2*5)+(1*2)=123
123 % 10 = 3
So 1114394-52-3 is a valid CAS Registry Number.

1114394-52-3Downstream Products

1114394-52-3Relevant articles and documents

Synthesis and evaluation of alkoxy-phenylamides and alkoxy-phenylimidazoles as potent sphingosine-1-phosphate receptor subtype-1 agonists

Evindar, Ghotas,Bernier, Sylvie G.,Kavarana, Malcolm J.,Doyle, Elisabeth,Lorusso, Jeanine,Kelley, Michael S.,Halley, Keith,Hutchings, Amy,Wright, Albion D.,Saha, Ashis K.,Hannig, Gerhard,Morgan, Barry A.,Westlin, William F.

scheme or table, p. 369 - 372 (2011/03/18)

In the design of potent and selective sphingosine-1-phosphate receptor agonists, we were able to identify two series of molecules based on phenylamide and phenylimidazole analogs of FTY-720. Several designed molecules in these scaffolds have demonstrated selectivity for S1P receptor subtype 1 versus 3 and excellent in vivo activity in mouse. Two molecules PPI-4621 (4b) and PPI-4691 (10a), demonstrated dose responsive lymphopenia, when administered orally.

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