111452-72-3

Basic information

• Product Name: 4-(Diphenylmethyl)-1-(2,3-epoxypropyl)piperazine
• Synonyms: 4-(Diphenylmethyl)-1-(2,3-epoxypropyl)piperazine;1-Benzhydryl-4-(oxiran-2-ylMethyl)piperazine
• CAS NO: 111452-72-3
• Molecular Formula: C₂₀H₂₄N₂O
• Molecular Weight: 308.42
• Product Categories: pharmacetical
• Mol File: 111452-72-3.mol
• Article Data: 7

Chemical Properties

• Melting Point: 99-102 °C
• Boiling Point: 423.9°Cat760mmHg
• Flash Point: 121.2°C
• Appearance: /
• Density: 1.148g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.606
• PKA: 6.93±0.10(Predicted)
• CAS DataBase Reference: 4-(Diphenylmethyl)-1-(2,3-epoxypropyl)piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(Diphenylmethyl)-1-(2,3-epoxypropyl)piperazine(111452-72-3)
• EPA Substance Registry System: 4-(Diphenylmethyl)-1-(2,3-epoxypropyl)piperazine(111452-72-3)

Safety Data

• Hazardous Substances Data: 111452-72-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C20H24N2O/c1-3-7-17(8-4-1)20(18-9-5-2-6-10-18)22-13-11-21(12-14-22)15-19-16-23-19/h1-10,19-20H,11-16H2

Upstream product

• 75591-24-1 1-(1-chloro-2-hydroxy-3-propanyl)-4-(diphenylmethyl)piperazine 
• 841-77-0 diphenylmethylpiperazine 
• 106-89-8 epichlorohydrin 
• 152333-94-3 glycidyl nosylate 
• 3132-64-7 1,2-Epoxy-3-bromopropane 

Downstream Products

• 163299-59-0 1-(4-Benzhydryl-piperazin-1-yl)-3-(3-[1.3,4]-thiadiazol-2-yl-phenoxy)propan-2-ol 
• 143759-85-7 1-(4-benzhydrylpiperazin-1-yl)-3-phenylsulfanylpropan-2-ol 
• 1198800-59-7 1-(4-benzhydrylpiperazin-1-yl)-3-benzylsulfanylpropan-2-ol 
• 1198800-62-2 1-(4-benzhydrylpiperazin-1-yl)-3-(methylphenylamino)propan-2-ol 
• 143759-62-0 1-[3-{2-(3,4-dimethoxyphenyl)ethylamino}-2-hydroxypropyl]-4-diphenylmethylpiperazine 
• 143759-60-8 1-diphenylmethyl-4-[2-hydroxy-3-(2-phenylethylamino)propyl]piperazine 
• 143759-61-9 1-diphenylmethyl-4-[2-hydroxy-3-{2-(2-methoxyphenyl)ethylamino}propyl]-piperazine 
• 143759-58-4 1-(4-benzhydrylpiperazin-1-yl)-3-phenylaminopropan-2-ol 

Relevant articles and documents

DIPHENYLMETHYL PIPERAZINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION USING SAME

The present invention provides: a novel compound which has a useful pharmacological action for treating heart failure or shock without increasing heart rate; and a pharmaceutical composition using the same. The present invention relates to a diphenylmethy

Anticancer agents

Disclosed herein is a method for suppressing the growth of cancer cells in a mammal in need of such treatment comprising administering to said mammal a cancer cell suppressing amount of a diphenylmethylpiperazine represented by the following general formu

Diphenylmethyl piperazine derivatives

Novel diphenylmethyl piperazine derivatives of this invention have a chemical structure represented by the following Formula [I]: STR1 wherein R represents STR2 The compounds have an effect of inhibiting the overcontraction and overextension of the myocar