111452-75-6

Basic information

• Product Name: Piperazine, 1-(diphenylmethyl)-4-(oxiranylmethyl)-, (S)-
• CAS NO: 111452-75-6
• Molecular Formula: C20H24N2O
• Molecular Weight: 308.423
• Mol File: 111452-75-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Piperazine, 1-(diphenylmethyl)-4-(oxiranylmethyl)-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperazine, 1-(diphenylmethyl)-4-(oxiranylmethyl)-, (S)-(111452-75-6)
• EPA Substance Registry System: Piperazine, 1-(diphenylmethyl)-4-(oxiranylmethyl)-, (S)-(111452-75-6)

Safety Data

• Hazardous Substances Data: 111452-75-6(Hazardous Substances Data)

Upstream product

• 841-77-0 diphenylmethylpiperazine 
• 115314-14-2 (2s)-(+)-glycidyl 3-nitrobenzenesulfonate 
• 113826-06-5 (R)-glycidyl tosylate 

Downstream Products

• 1258710-26-7 (R)-1-(4-benzhydryl-piperazin-1-yl)-3-(phenethylamino)-propan-2-ol 
• 1258710-35-8 (R)-1-(4-benzhydryl-piperazin-1-yl)-3-((cyclopropylmethyl)-amino)-propan-2-ol 

Relevant articles and documents

BACE1 inhibitory activities of enantiomerically pure, variously substituted N-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropyl) arylsulfonamides

β-Secretase (BACE1) has been widely recognized as one of the possible therapeutic targets for the treatment of Alzheimer's disease. In this paper, we report the synthesis and the BACE1 inhibitory activity of new, variously substituted N-(3-(4-benzhydrylpi