111468-65-6Relevant articles and documents
Versatile palladium(II)-catalyzed Negishi coupling reactions with functionalized conjugated alkenyl chlorides
Peyrat, Jean-Fran?ois,Thomas, Emmanuel,L'Hermite, Nathalie,Alami, Mouad,Brion, Jean-Daniel
, p. 6703 - 6707 (2003)
Under palladium catalysis, we found that organozincate reagents, generated in situ, by reaction of Grignard compounds with less than molar amounts of zinc chloride, in the presence of conjugated alkenyl chlorides, give rapidly and cleanly the corresponding coupling product in high yields. In this way, aryl as well as primary and secondary alkyl substituents have been introduced successfully. The selectivity of the reaction allows to prepare various functionalized conjugated enynes and dienes from chloroenyne and chlorodiene derivatives bearing a functional group.
Enyne synthesis through a modified Sonogashira cross-coupling reaction catalyzed by cyclopalladated complexes
Huang, Mengmeng,Feng, Yujian,Wu, Yangjie
experimental part, p. 376 - 381 (2012/01/14)
A series of conjugated enynes were successfully synthesized by the palladacycle-catalyzed modified Sonogashira cross-coupling reaction of β-bromostyrene and terminal alkynes. The reaction proceeds smoothly in DMSO at 40 °C to give the corresponding produc
CuI-catalyzed Suzuki-Miyaura and Sonogashira cross-coupling reactions using DABCO as ligand
Li, Jin-Heng,Li, Ji-Lan,Wang, De-Ping,Pi, Shao-Feng,Xie, Ye-Xiang,Zhang, Man-Bo,Hu, Xi-Chao
, p. 2053 - 2057 (2007/10/03)
In the presence of TBAB, CuI-catalyzed Suzuki-Miyaura cross-coupling of vinyl halides and aryl halides with arylboronic acids was conducted smoothly to afford the corresponding diarylethenes and polyaryls in moderate to good yields using DABCO (1,4-diazabicyclo[2.2.2]octane) as the ligand. We also found that the inexpensive CuI/DABCO catalytic system was effective for Sonogashira cross-couplings of aryl halides and vinyl halides. A variety of aryl halides and vinyl halides including activated aryl chlorides underwent the coupling with terminal alkynes in moderate to excellent yields.