111478-84-3 Usage
Description
1,8-Diethyl-1,3,4,9-tetrahydro-4-oxo-pyrano[3,4-b]indole-1-acetic Acid Methyl Ester is a complex organic compound that is a derivative of Etodolac metabolite. It is characterized by its chemical structure, which includes a pyranoindole core with various substituents, and is presented as a white solid.
Uses
Used in Pharmaceutical Industry:
1,8-Diethyl-1,3,4,9-tetrahydro-4-oxo-pyrano[3,4-b]indole-1-acetic Acid Methyl Ester is used as a pharmaceutical compound for its potential therapeutic applications. As a derivative of Etodolac metabolite, it may exhibit anti-inflammatory, analgesic, or other beneficial properties that can be harnessed in the development of new drugs or therapies.
Used in Chemical Research:
In the field of chemical research, 1,8-Diethyl-1,3,4,9-tetrahydro-4-oxo-pyrano[3,4-b]indole-1-acetic Acid Methyl Ester can be used as a starting material or intermediate in the synthesis of more complex molecules. Its unique structure may allow for the development of novel chemical entities with specific applications in various industries.
Used in Material Science:
The compound may also find applications in material science, where its properties can be explored for potential use in the development of new materials with specific characteristics, such as improved stability, reactivity, or other desirable traits.
Check Digit Verification of cas no
The CAS Registry Mumber 111478-84-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,1,4,7 and 8 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 111478-84:
(8*1)+(7*1)+(6*1)+(5*4)+(4*7)+(3*8)+(2*8)+(1*4)=113
113 % 10 = 3
So 111478-84-3 is a valid CAS Registry Number.
InChI:InChI=1/C18H21NO4/c1-4-11-7-6-8-12-15-13(20)10-23-18(5-2,9-14(21)22-3)17(15)19-16(11)12/h6-8,19H,4-5,9-10H2,1-3H3
111478-84-3Relevant articles and documents
Etodolac, a novel antiinflammatory agent. The syntheses and biological evaluation of its metabolites
Humber,Ferdinandi,Demerson,Ahmed,Shah,Mobilio,Sabatucci,De Lange,Labbadia,Hughes,DeVirgilio,Neuman,Chau,Weichman
, p. 1712 - 1719 (2007/10/02)
The syntheses of five metabolites of the antiinflammatory drug etodolac (1,8-diethyl-1,3,4,9-tetrahydropyrano-[3,4-b]indole-1-acetic acid) are described, viz. 6-hydroxyetodolac, N-methyletodolac, 4-ureidoetodolac, 8-(1'-hydroxy)etodolac, and 4-oxoetodolac. These syntheses were used to confirm the identities of the metabolites. The metabolites themselves, as well as the previously reported metabolite 7-hydroxyetodolac, were tested in a rat adjuvant edema model and in vitro for their capacity to block prostaglandin production in chondrocyte cells. All either were inactive or possessed only marginal activity. The isolation of N-methyletodolac and 4-oxoetodolac from human and rat urine, respectively, is also described.
