1114883-80-5Relevant academic research and scientific papers
Sequential rhodium-, silver-, and gold-catalyzed synthesis of fused dihydrofurans
Wang, Hengbin,Denton, Justin R.,Davies, Huw M. L.
supporting information; experimental part, p. 4316 - 4319 (2011/10/05)
A triple cascade process was developed for the rapid synthesis of polycyclic benzo-fused dihydrofurans. The first step is a rhodium-catalyzed cyclopropanation of α-aryldiazoketones with alkenes. This is followed by a silver-catalyzed ring expansion to dih
Enantioselective reactions of donor/acceptor carbenoids derived from α-aryl-α-diazoketones
Denton, Justin R.,Davies, Huw M. L.
supporting information; experimental part, p. 787 - 790 (2009/09/06)
The reaction of a variety of α-aryl-α-diazo ketones with activated olefins, catalyzed by the adamantyl glycine-derived dirhodium complex Rh2(S-PTAD)4, generates cyclopropyl ketones with high diastereoselectivity (up to >95:5 dr) and enantioselectivity (up to 98% ee). Intermolecular C-H functionalization of 1,4-cyclohexadiene by means of carbenoid-induced C-H insertion was also possible with this type of carbenoid.
