111504-86-0Relevant academic research and scientific papers
ASYMMETRIC α-AMIDOALKYLATION. SYNTHESIS OF α-SUBSTITUTED PIPERIDINES OF HIGH ENANTIOMERIC PURITY
Wanner, Klaus Th.,Kaertner, Annerose
, p. 921 - 924 (2007/10/02)
A stereoselective α-amidoalkylation was performed employing the chiral and cyclic enamide 1.The resulting amides 6 were employed in the synthesis of the title products.
Asymmetric α-Amidoalkylation. Syntheses of Enantiomerically Pure α-Substituted Piperidines with 1-Camphanoyl-1,2,3,4-tetrahydropyridine
Wanner, Klaus Th.,Kaertner, Annerose
, p. 1253 - 1267 (2007/10/02)
In a novel asymmetric synthesis the homochiral enamide 1 is coupled with the silyl enol ethers 5a-c in a diastereoselective fashion to afford the amidoalkylation products 6/7a-c.These are employed in the synthesis of enantiomerically pure, in α-position R
