39158-85-5

Basic information

• Product Name: Silane, trimethyl[(2-methyl-1-phenyl-1-propenyl)oxy]-
• CAS NO: 39158-85-5
• Molecular Formula: C13H20OSi
• Molecular Weight: 220.387
• Mol File: 39158-85-5.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: Silane, trimethyl[(2-methyl-1-phenyl-1-propenyl)oxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: Silane, trimethyl[(2-methyl-1-phenyl-1-propenyl)oxy]-(39158-85-5)
• EPA Substance Registry System: Silane, trimethyl[(2-methyl-1-phenyl-1-propenyl)oxy]-(39158-85-5)

Safety Data

• Hazardous Substances Data: 39158-85-5(Hazardous Substances Data)

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 611-70-1 phenyl isopropyl ketone 
• 27607-77-8 trimethylsilyl trifluoromethanesulfonate 
• 7449-74-3 N-methyl-N-trimethylsilylacetamide 
• 10409-54-8 2-bromo-2-methyl-1-phenyl-propan-1-one 
• 78279-92-2 2,3,5,6-tetramethyl-1,4-bis(trimethylsilyl)-1,4-diaza-2,5-cyclo-hexadiene 
• 5170-76-3 2-methyl-1-phenyl-1-acetoxy-1-propene 
• 684-26-4 N,N-dimethyl-N',N'-bis(trimethylsilyl)hydrazine 
• 74-88-4 methyl iodide 
• 5908-41-8 benzoyltrimethylsilane 
• 4170-69-8 isopropyl phenyl sulfoxide 

Downstream Products

• 7476-41-7 2-methyl-1-oxo-1-phenylpropan-2-yl acetate 
• 611-70-1 phenyl isopropyl ketone 
• 130010-27-4 (1S,4R)-1-<(1S)-1,2,3,4-Tetrahydro-6,7-dimethoxy-1-(1,1-dimethyl-2-oxo-2-phenyl-1-ethyl)-2-isoquinolylcarbonyl>-4,7,7-trimethyl-2-oxa-bicyclo<2.2.1>heptan-3-one 
• 129958-84-5 (1S,4R)-1-<(1R)-1,2,3,4-Tetrahydro-6,7-dimethoxy-1-(1,1-dimethyl-2-oxo-2-phenyl-1-ethyl)-2-isoquinolylcarbonyl>-4,7,7-trimethyl-2-oxa-bicyclo<2.2.1>heptan-3-one 
• 83180-98-7 2,2-Dimethyl-1-phenyl-3-phenylsulfanyl-hex-5-en-1-one 
• 83180-99-8 2,2,5-Trimethyl-1-phenyl-3-phenylsulfanyl-hex-5-en-1-one 
• 80737-55-9 3,3-Dimethyl-c-2-phenyl-t-2-(trimethylsiloxy)-r-1-cyclopropancarbonsaeure-methylester 
• 80737-56-0 3,3-Dimethyl-t-2-phenyl-c-2-(trimethylsiloxy)-r-1-cyclopropancarbonsaeure-methylester 
• 103003-83-4 methyl 3-((2-benzoylpropyl)seleno)-2,2-dimethylpropionate 
• 111612-20-5 (1S,4R)-1-<(2R)-2-(2-Methyl-3-oxo-3-phenyl-2-propyl)-1-piperidylcarbonyl>-4,7,7-trimethyl-2-oxa-bicyclo<2.2.1>heptan-3-on 
• 111504-86-0 (1S,4R)-1-<(2S)-2-(2-Methyl-3-oxo-3-phenyl-2-propyl)-1-piperidylcarbonyl>-4,7,7-trimethyl-2-oxa-bicyclo<2.2.1>heptan-3-on 
• 147933-14-0 3-(1-benzoyl-1-methylethyl)-4-methoxycyclobut-3-ene-1,2-dione 
• 147932-85-2 3-(1-benzoyl-1-methylethyl)-4-(diethylamino)cyclobut-3-ene-1,2-dione 
• 7473-98-5 2-hydroxy-2-methylpropiophenone 

Relevant articles and documents

β-Diazocarbonyl Compounds: Synthesis and their Rh(II)-Catalyzed 1,3 C?H Insertions

Herein, we describe the first electrophilic diazomethylation of ketone silyl enol ethers with diazomethyl-substituted hypervalent iodine reagents that gives access to unusual β-diazocarbonyl compounds. The potential of this unexplored class of diazo compounds for the development of new reactions was demonstrated by the discovery of a rare Rh-catalyzed intramolecular 1,3 C?H carbene insertion that led to complex cyclopropanes with excellent stereocontrol.

Organosilicon Reducing Reagents for Stereoselective Formations of Silyl Enol Ethers from α-Halo Carbonyl Compounds

Salt-free stereoselective synthesis of silyl enol ethers was achieved by treating α-halo carbonyl compounds with 2,3,5,6-tetramethyl-1,4-bis(trimethylsilyl)-1,4-dihydropyrazine. In this reaction, easily removable trimethylsilyl halides and 2,3,5,6-tetramethylpyrazine were generated as the reaction byproducts. Due to the inertness of the reaction byproducts, we found a one-pot transformation of the in situ generated silyl enol ethers into various α-functionalized carbonyls by reaction with Togni-II reagent or aldehydes.

Direct use of esters in the Mukaiyama aldol reaction: A powerful and convenient alternative to aldehydes

An indium triiodide catalyst promoted the direct transformation from esters to β-hydroxycarbonyl compounds using hydrosilanes and silyl enolates by a one-stage process. Various esters were applicable, and the high chemoselectivity of this system brings compatibility to many functional groups: alkenyl, alkynyl, chloro, and hydroxy.