111550-09-5

Basic information

• Product Name: (Ξ)-3,4-methylenedioxy-β-(toluene-4-sulfonyl)-styrene
• Synonyms: (Ξ)-3,4-methylenedioxy-β-(toluene-4-sulfonyl)-styrene
• CAS NO: 111550-09-5
• Molecular Weight: 302.351
• Mol File: 111550-09-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Ξ)-3,4-methylenedioxy-β-(toluene-4-sulfonyl)-styrene(CAS DataBase Reference)
• NIST Chemistry Reference: (Ξ)-3,4-methylenedioxy-β-(toluene-4-sulfonyl)-styrene(111550-09-5)
• EPA Substance Registry System: (Ξ)-3,4-methylenedioxy-β-(toluene-4-sulfonyl)-styrene(111550-09-5)

Safety Data

• Hazardous Substances Data: 111550-09-5(Hazardous Substances Data)

Upstream product

• 120-57-0 piperonal 
• 3937-96-0 tosylacetic acid 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 6543-34-6 benzo[1,3]dioxol-5-yl-acetaldehyde 

Relevant articles and documents

Copper(II) Acetate Mediated Synthesis of 3-Sulfonyl-2-aryl-2 H -chromenes

This paper describes a concise, easy-operation, high-yielding method for the synthesis of 3-sulfonyl-2-aryl-2 H -chromenes by a one-pot, straightforward two-step synthetic route, which includes (i) Cu(OAc) 2 /PyBOP-mediated intermolecular [4+2] annulation of substituted salicylic acids with β-sulfonylstyrenes in the presence of DMAP in refluxing DMF, and (ii) sequential O -alkylation of the resulting sulfonylflavanones with n -butyl bromide. A plausible mechanism is proposed and discussed. This protocol provides a highly effective annulation via one carbon-oxygen (C-O) and one carbon-carbon (C-C) bond formations.