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1115867-62-3

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1115867-62-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1115867-62-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,1,5,8,6 and 7 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1115867-62:
(9*1)+(8*1)+(7*1)+(6*5)+(5*8)+(4*6)+(3*7)+(2*6)+(1*2)=153
153 % 10 = 3
So 1115867-62-3 is a valid CAS Registry Number.

1115867-62-3Downstream Products

1115867-62-3Relevant articles and documents

Structure-activity relationship studies on rhodamine B-based fluorogenic probes and their activation by anticancer platinum(II) compounds

Ong, Jun Xiang,Yap, Jian Yu,Yap, Siew Qi,Ang, Wee Han

, p. 272 - 278 (2015)

Fluorescence microscopy has emerged as an attractive technique for imaging intracellular Pt species arising from exposure to clinical anticancer drugs such as cisplatin. A rhodamine-B based fluorogenic probe termed Rho-DDTC can be activated selectively in the presence of Pt(II) compounds, and possesses the ability to discriminate Pt(II) species from Pt(IV) carboxylate prodrug complexes, thereby providing a unique platform to investigate the reduction of these Pt(IV) complexes after cell entry. In this report, we seek to establish the mechanism of activation of Rho-DDTC through a structure-activity relationship study on its structural analogues.

A dual functional probe for "turn-on" fluorescence response of Pb2+ and colorimetric detection of Cu2+ based on a rhodamine derivative in aqueous media

Li, Min,Jiang, Xiu-Juan,Wu, Hui-Hui,Lu, Hong-Lin,Li, Hai-Yang,Xu, Hong,Zang, Shuang-Quan,Mak, Thomas C. W.

, p. 17326 - 17334 (2015)

A dual functional probe L based on rhodamine was devised and synthesized. Probe L can sense Pb2+ and Cu2+ in aqueous solution through two approaches: a significant fluorescence enhancement caused by Pb2+ and a visible color change from colorless to orchid induced by Cu2+. Competitive experiments showed that probe L had high fluorescence sensitivity for Pb2+ and excellent colorimetric selectivity for Cu2+ over many environmentally relevant ions. The mechanisms of L for sensing Pb2+ and Cu2+ have been well demonstrated by ESI-MS, 1H NMR titration, IR, the crystal structure of L-Pb2+ and density functional theory calculation of L-Cu2+. In addition, fluorescence image detection of Pb2+ in living cells displayed an enhanced fluorescence effect.

Hg2+-selective dual signaling probe based on a thio-functionalized rhodamine B hydroxamic acid

Jeong, Yong Ae,Choi, Jiyoung,Chang, Suk-Kyu

, p. 4919 - 4922 (2015)

Abstract A new Hg2+-selective signaling system based on a thio-functionalized rhodamine B hydroxamic acid was investigated. A thio-analogue of rhodamine B hydroxamic acid had a distinct Hg2+-selective signaling behavior in aqueous solution, whereas its parent hydroxamic acid was completely unreactive toward any metal ions. Selective chromogenic and fluorogenic signaling of Hg2+ by the thio-functionalized rhodamine B hydroxamic acid in aqueous solution was possible with a detection limit of 1.0 × 10-6 M. Hg2+ determination based on paper test strips was conducted as a practical application.

A fluorescent probe for investigating the activation of anticancer platinum(IV) prodrugs based on the cisplatin scaffold

Montagner, Diego,Yap, Siew Qi,Ang, Wee Han

, p. 11785 - 11789 (2013)

Watching closely: A fluorescent probe was engineered to detect the clinically relevant platinum drug cisplatin within a complex cellular environment, thus providing a direct means for visualizing its cell entry and the activation of platinum(IV) prodrugs in cancer cells. Copyright

A six-membered-ring incorporated Si-rhodamine for imaging of copper(II) in lysosomes

Wang, Baogang,Cui, Xiaoyan,Zhang, Zhiqiang,Chai, Xiaoyun,Ding, Hao,Wu, Qiuye,Guo, Zhongwu,Wang, Ting

, p. 6720 - 6728 (2016)

The regulation of copper homeostasis in lysosomes of living cells is closely related to various physiological and pathological processes. Thus, it is of urgent need to develop a fluorescent probe for selectively and sensitively monitoring the location and

A mild method for synthesizing carboxylic acids by oxidation of aldoximes using hypervalent iodine reagents

Nakamura, Akira,Kanou, Hodaka,Tanaka, Junki,Imamiya, Akira,Maegawa, Tomohiro,Miki, Yasuyoshi

supporting information, p. 541 - 544 (2018/02/07)

A mild oxidation method for the conversion of aldoximes to carboxylic acids was developed mediated by hypervalent iodine reagents. This method covers a wide range of functionalized aldoximes and proceeds under mild conditions, utilizing PhI(OH)OTs as an oxidant.

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