1115974-29-2Relevant academic research and scientific papers
Synthesis and in vitro antimicrobial activity of novel 2-(3-oxo-1,3- diarylpropylthio)acetic acid derivatives
Gezegen, Hayreddin,Karaman, Isa,Ceylan, Mustafa,Dilmac, Merve
, p. 893 - 900 (2012/10/30)
A series of novel 2-(3-oxo-1,3-diarylpropylthio)acetic acid derivatives (3a-l) were prepared by base catalyzed addition of thioglycolic acid to chalcones (1a-l). The antibacterial activities of synthesized compounds were screened against human pathogenic microorganisms by employing the disk-diffusion technique. For the active compounds, also minimum inhibitory concentrations (MICs) were determined.
