111599-77-0Relevant academic research and scientific papers
Synthesis, experimental and theoretical NMR study of 2′- hydroxychalcones bearing a nitro substituent on their B ring
Barros, Ana I.R.N.A.,Silva, Artur M.S.,Alkorta, Ibon,Elguero, José
, p. 6513 - 6521 (2004)
The synthesis of several 2′-hydroxynitrochalcones has been accomplished by an aldol reaction of equimolar amounts of the appropriate 2′-hydroxyacetophenones with nitrobenzaldehydes in alkaline medium. The reaction of 2′-hydroxyacetophenones bearing a 6′-methoxy with 2- or 4-nitrobenzaldehydes gave the expected 2′-hydroxynitrochalcones and also 4-methoxynitroaurones, being the latter ones the unique reaction products when using 2molar equiv of nitrobenzaldehydes. The reaction mechanisms for the formation of both products are discussed. The 13C NMR chemical shifts have been discussed first by means of an empirical additive model and then by comparison with GIAO/B3LYP calculated absolute shieldings.
NOVEL ONE POT CONVENIENT SYNTHESIS OF 3- BENZYLIDENE-2-PHENYL-2,3-DIHYDRO-4H-1-BENZOPYRAN-4-ONES
Chawla, H. Mohindra,Sharma, S. Kumar
, p. 1527 - 1534 (2007/10/02)
A novel one pot good yield synthesis of 3-benzylidene-2-phenyl-2,3-dihydro-4H-1-benzopyran-4-ones by the condensation of o-hydroxyacetophenones with aromatic aldehydes has been described and the new compounds were identified by their chemical, analytical and spectroscopic data.
