1116-13-8

Usage

Uses

Used in Personal Care Products:
N-LAUROYL-L-ASPARTIC ACID is used as a surfactant for its superior cleansing and foaming capabilities, making it suitable for a variety of products such as shampoos, body washes, and facial cleansers.
Used in Cosmetics:
N-LAUROYL-L-ASPARTIC ACID is used as a skin conditioning agent to provide moisturization and softness to the skin, which is beneficial in the formulation of moisturizers, lotions, and creams.
Used in the Cosmetics Industry:
N-LAUROYL-L-ASPARTIC ACID is used as a surfactant and skin conditioning agent for its ability to enhance the cleansing and moisturizing properties of cosmetic products, ensuring both effectiveness and skin comfort.
Safety:
N-LAUROYL-L-ASPARTIC ACID is considered safe for use in cosmetics and personal care products when used according to established guidelines, ensuring the well-being of consumers and the efficacy of the products in which it is incorporated.

Upstream product

• 112-16-3 n-dodecanoyl chloride 
• 3792-50-5 L-aspartic acid disodium salt 
• 1182-15-6 N^α-lauryl-L-aspartic acid dibenzyl ester 
• 143-07-7 lauric acid 
• 3792-50-5 L-aspartic acid monosodium salt 
• 56-84-8 L-Aspartic acid 

Relevant academic research and scientific papers

Preparation method and application of amido carboxylic acid compound

The invention discloses a preparation method and application of an amido carboxylic acid compound. The preparation method comprises the step of subjecting organic carboxylic acid with a structure represented by a formula (I) shown in the description and an amino acid compound with a structure represented by a formula (II) shown in the description to a grinding reaction in the presence of a coupling reagent, thereby preparing the amido carboxylic acid compound with a structure represented by a formula (III) shown in the description. The product prepared by the method is high in yield, is energy-saving and environmentally friendly and does not need aftertreatment. According to the application, the amido carboxylic acid compound is applied to mineral flotation separation as a collector, and the collector has relatively high collection capability and relatively good selectivity and is particularly applicable to the flotation separation of minerals such as wolframite, scheelite, rare earthminerals, cassiterite, ilmenite, bauxite, manganese oxide ores, phosphorite and fluorite.

DETERGENT COMPOSITION

There is provided a cleansing composition which has creamy foaming and excellent cleansing power, provides no stretched feeling of skin after rinsing and a refreshed feeling of skin, is excellent in storage stability and exhibits no reduction in physical properties, formation of precipitates and yellowing during a long-term storage period by combining N-acyl-aspartic acid or a salt thereof and N-acyl-diaspartic acid or a salt thereof, which have the same molecular structure of the N-acyl group, with a higher fatty acid or a salt thereof which has the same alkyl group as that of the above described N-acyl residue.

Isolation and total synthesis of gymnastatin N, a POLO-like kinase 1 active constituent from the fungus Arachniotus punctatus

A high throughput screen against POLO-like kinase 1 (Plk1), an anti-cancer target, identified an active extract from the fungus Arachniotus punctatus. Bioassay guided fractionation led to the isolation of the new natural product, gymnastatin N (1) and the known compound aranorosinol A (2) with IC50 values of 13 and 118 μM, respectively. A 12′-hydroxy analog of gymnastatin N, 3, was also isolated as a minor component. Gymnastatin N (1) was found to be a 52:48 mixture of (1S,6′R) and (1R,6′R) diastereomers, by synthesis of the four possible diastereomers and comparison of the optical rotation and chiral HPLC profile of each diastereoisomer with the natural product. Analogues of 1 were synthesized and evaluated against the Plk1 assay and these SAR studies suggested that the diene and free carboxylic acid moieties might be responsible for its bioactivity. Graphical Abstract.

Cosmetic composition

A composition suitable for topical application to mammalian skin and hair for inducing, maintaining or increasing hair growth comprises a hair growth promoter chosen from glutamine derivatives and salts thereof. The composition preferably also comprises an activity enhancer which may be chosen from hair growth stimulants, penetration enhancers and cationic polymers.

Cosmetic composition containing DOPA derivatives

A composition for topical application to human hair or skin contains a chemical analogue of dihydroxyphenyl alanine (DOPA). This chemical analogue can be absorbed by skin or by a hair follicle and metabolised in-vivo, thus leading to the formation of melanin in skin or to the growth of melanin-pigmented hair. Consequently the composition can give controlled skin darkening to mimic sun-induced tanning or can bring about the growth of dar hair in place of the grey or white hair.

Cosmestic composition

A composition suitable for topical application to mammalian skin and hair for inducing, maintaining or increasing hair growth comprises a hair growth promoter chosen from glutamic acid derivatives and salts thereof. The composition preferably also comprises an activity enhancer which may be chosen from hair growth stimulants, penetration enhancers and cationic polymers.

Hair growth composition containing citric acid esters

Triesters of citric acid are used for inducing, maintaining or increasing hair growth. Compositions for topical application to mammalian hair or scalp comprise an effective amount of from 1% to 99% by weight of an ester of citric acid having the structure (1): where, R1, R2 and R3 each independently represent a branched or unbranched alkyl, alkenyl, aryl, alkylaryl or arylalkyl group, each said group having from 1 to 18 carbon atoms, R4 represents -H, or a branched or unbranched saturated or unsaturated acyl, alkyl, aryl, alkylaryl or aylalkyl group having from 1 to 18 carbon atoms, in the presence of a cosmetically acceptable vehicle for the citric acid ester and in the absence of solid absorbent for the ester;, said effective amount of said ester being sufficient to increase hair growth in the rat, when said composition is applied topically thereto over a period of no more than three months, by at least 10% more than that obtainable using a control composition from which the said ester has been omitted, in accordance with the Rat Hair Growth Test.

Fatty Acid Derivatives of Acidic Amino Acids as Potential Antibiotics

The synthesis of fatty acid derivatives (1-8) of acidic amino acids is reported and their bioactivity tested.At higher concentrations, these compounds cause denaturation of haemoglobin.None of these compounds inhibit E. coli growth up to 2.5 mg/ml.

Melting Behaviour of Some Pure N-Acyl Amino Acids and Peptides

Fifty three tlc pure N-acyl amino acids were synthesized by Schotten-Baumann reaction from glc pure odd and even chain fatty acids and chromatographycally homogeneous amino acids and a few N-acyl peptides were prepared through the carboxylic carbonic anhydride intermediates.The melting points are reported and discussed.