111603-56-6

Basic information

• Product Name: ethyl 2-<2-amino-5-(ethoxycarbonyl)-4-thiazolylthio>acetoacetate
• Synonyms: ethyl 2-<2-amino-5-(ethoxycarbonyl)-4-thiazolylthio>acetoacetate
• CAS NO: 111603-56-6
• Molecular Weight: 332.401
• Mol File: 111603-56-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 2-<2-amino-5-(ethoxycarbonyl)-4-thiazolylthio>acetoacetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-<2-amino-5-(ethoxycarbonyl)-4-thiazolylthio>acetoacetate(111603-56-6)
• EPA Substance Registry System: ethyl 2-<2-amino-5-(ethoxycarbonyl)-4-thiazolylthio>acetoacetate(111603-56-6)

Safety Data

• Hazardous Substances Data: 111603-56-6(Hazardous Substances Data)

Upstream product

• 333-20-0 potassium thioacyanate 
• 609-15-4 ethyl 2-chloro-3-oxo-butyrate 

Downstream Products

• 32955-21-8 2-amino-thiazole-5-carboxylic acid ethyl ester 

Relevant articles and documents

Pseudohalogen chemistry. XI. Some aspects of the chemistry of octhiocyanato-β-dicarbonyl compounds

Enolised α-thiocyanato-β-dicarbonyl compounds dimerise in ethanol at room temperature to give tautomeric 4,5-disubstituted 2-amino- and 2-acetamido-thiazoles by a C-S-C + C-N cyclisation. Tautomerism is due to the unusual 4-(β-dicarbonyl-α-thio) substituent. Competing intramolecular cyclisations lead to minor amounts of heterocycles containing the thiazole and/or oxathiole ring systems.