1116571-38-0

Basic information

• Product Name: 5-(1,3-benzodioxol-5-ylmethylene)-2-(2,4-dichloro-5-fluorophenyl)-1,3-thiazolo[3,2-b]-1,2,4-triazol-6(5H)-one
• CAS NO: 1116571-38-0
• Molecular Weight: 436.25
• Mol File: 1116571-38-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(1,3-benzodioxol-5-ylmethylene)-2-(2,4-dichloro-5-fluorophenyl)-1,3-thiazolo[3,2-b]-1,2,4-triazol-6(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(1,3-benzodioxol-5-ylmethylene)-2-(2,4-dichloro-5-fluorophenyl)-1,3-thiazolo[3,2-b]-1,2,4-triazol-6(5H)-one(1116571-38-0)
• EPA Substance Registry System: 5-(1,3-benzodioxol-5-ylmethylene)-2-(2,4-dichloro-5-fluorophenyl)-1,3-thiazolo[3,2-b]-1,2,4-triazol-6(5H)-one(1116571-38-0)

Safety Data

• Hazardous Substances Data: 1116571-38-0(Hazardous Substances Data)

Upstream product

• 120-57-0 piperonal 
• 306298-83-9 5-(2,4-dichloro-5-fluorophenyl)-4H-1,2,4-triazole-3-thiol 
• 79-11-8 chloroacetic acid 

Relevant articles and documents

Synthesis, antiinflammatory and antimicrobial activities of some 2,4-dichloro-5-fluorophenyl substituted arylidenetriazolothiazolidinones

A series of 2,4-dichloro-5-fluorophenyl substituted arylidenetriazolothiazolidinones were obtained by one-pot reaction of 3-(2,4-dichloro-5-fluorophenyl)-4H-1,2,4-triazole-5-thiol with substituted benzaldehydes and monochloroacetic acid in the presence of acetic anhydride, acetic acid, and sodium acetate. The structures of the newly synthesized compounds were characterized and confirmed by IR, 1H NMR, mass spectra, and elemental analysis. Compounds bearing the 4-methylthiophenyl, 3,4-methylenedioxyphenyl, and 2,3,5-trichlorophenyl moiety showed excellent antiinflammatory activity. The antimicrobial screening studies revealed that compounds with 4-anisyl, 4-methylthiophenyl, 3,4-methylenedioxyphenyl, and 2,3,5-trichlorophenyl at position 5 of the arylidenetriazolothiazolidinone moiety showed excellent activity against all tested strains at 6.25 μg cm-3 concentrations.