306298-83-9

Upstream product

• 86393-34-2 2,4-dichloro-5-fluorobenzoyl chloride 

Downstream Products

• 1116571-38-0 5-(1,3-benzodioxol-5-ylmethylene)-2-(2,4-dichloro-5-fluorophenyl)-1,3-thiazolo[3,2-b]-1,2,4-triazol-6(5H)-one 
• 1116571-39-1 2-(2,4-dichloro-5-fluorophenyl)-5-(2,3,5-trichlorobenzylidene)-1,3-thiazolo[3,2-b]-1,2,4-triazol-6(5H)-one 
• 1116571-35-7 5-(4-chlorobenzylidene)-2-(2,4-dichloro-5-fluorophenyl)-1,3-thiazolo[3,2-b]-1,2,4-triazol-6(5H)-one 
• 1116571-32-4 2-(2,4-dichloro-5-fluorophenyl)-5-(4-methoxybenzylidene)-1,3-thiazolo[3,2-b]-1,2,4-triazol-6(5H)-one 
• 1116571-37-9 5-(2,4-dichlorobenzylidene)-2-(2,4-dichloro-5-fluorophenyl)-1,3-thiazolo[3,2-b]-1,2,4-triazol-6(5H)-one 
• 1116571-34-6 2-(2,4-dichloro-5-fluorophenyl)-5-(4-(dimethylamino)-benzylidene)-1,3-thiazolo[3,2-b]-1,2,4-triazol-6(5H)-one 
• 1116571-33-5 2-(2,4-dichloro-5-fluorophenyl)-5-(4-(methylthio)-benzylidene)-1,3-thiazolo[3,2-b]-1,2,4-triazol-6(5H)-one 
• 1116571-36-8 5-(2-chloro-5-nitrobenzylidene)-2-(2,4-dichloro-5-fluorophenyl)-[1,3]-thiazolo[3,2-b]-1,2,4-triazol-6(5H)-one 
• 1144511-85-2 C₁₆H₇Cl₄F₂N₃OS 
• 1144511-71-6 C₁₇H₁₂Cl₂FN₃O₂S 
• 1144511-75-0 C₁₆H₉Cl₂F₂N₃OS 
• 1144511-79-4 C₁₆H₉BrCl₂FN₃OS 
• 1144511-77-2 C₁₆H₉Cl₃FN₃OS 
• 1144511-73-8 C₁₇H₁₂Cl₂FN₃OS 

Relevant academic research and scientific papers

Synthesis, analgesic, anti-inflammatory and antimicrobial studies of 2,4-dichloro-5-fluorophenyl containing thiazolotriazoles

A series of 2,4-dichloro-5-fluorophenyl containing thiazolotriazoles (1) were synthesized starting from 3-(2,4-dichloro-5-fluorophenyl)-4H-1,2,4-triazole-3-thiol (5). The newly synthesized compounds were characterized by IR, 1H NMR, mass and el

Synthesis, antiinflammatory and antimicrobial activities of some 2,4-dichloro-5-fluorophenyl substituted arylidenetriazolothiazolidinones

A series of 2,4-dichloro-5-fluorophenyl substituted arylidenetriazolothiazolidinones were obtained by one-pot reaction of 3-(2,4-dichloro-5-fluorophenyl)-4H-1,2,4-triazole-5-thiol with substituted benzaldehydes and monochloroacetic acid in the presence of acetic anhydride, acetic acid, and sodium acetate. The structures of the newly synthesized compounds were characterized and confirmed by IR, 1H NMR, mass spectra, and elemental analysis. Compounds bearing the 4-methylthiophenyl, 3,4-methylenedioxyphenyl, and 2,3,5-trichlorophenyl moiety showed excellent antiinflammatory activity. The antimicrobial screening studies revealed that compounds with 4-anisyl, 4-methylthiophenyl, 3,4-methylenedioxyphenyl, and 2,3,5-trichlorophenyl at position 5 of the arylidenetriazolothiazolidinone moiety showed excellent activity against all tested strains at 6.25 μg cm-3 concentrations.

Fluorine containing heterocyclic compounds: Synthesis of 6-substituted-2-substituted-aryl-1,2,4-triazolo[5,1-b] 1,3,5-thiadiazin-7-one derivatives

A group of heterocylic compounds of condensed triazole-thiadiazinone derivatives containing fluorine (IIIa-h) were obtained in good yields by the reactions of the corresponding 3-aryl-5-mercapto-1,2,4-triazole (IIa-d) with N-substituted-N-chloromethyl carbamoyl chloride (I) in the presence of potassium carbonate in N,N-dimethylformamide at room temperature. Cyclization of 3-(2,3,5-trifluoro-4-methoxyl)phenyl-5-mercapto-1,2,4-triazole (IIe) with I was difficult due to an intermolecular hydrogen bond of IIe. The structures of the compounds synthesized were confirmed by IR, MS, 1H NMR and elemental analyses. Fungicidal and insecticidal activities of these compounds were also studied.