1116654-52-4Relevant academic research and scientific papers
Glycoconjugates and use thereof as vaccine against Shigella flexneri serotype 3a and X
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, (2014/09/03)
The present invention relates to compounds derived from sugars which reproduce the epitopes of Shigella flexneri serotypes 3a and X and to the use thereof for the preparation of vaccine compositions. More specifically, the subject matter of the present in
Synthesis of two tetra- and four pentasaccharide fragments of Shigella flexneri serotypes 3a and X O-antigens from a common tetrasaccharide intermediate
Boutet, Julien,Mulard, Laurence A.
experimental part, p. 5526 - 5542 (2009/05/11)
Relying on trichloroacetimidate chemistry, six tetra- and pentasaccharide fragments of the {2)-[α-D-Glcp-(1→3)]-α-L-Rhap-(1→2)- α-L-Rhap-(1→3)-[Ac→2]-α-L-Rhap-(1→3) -β-D-GlcpNAc-(1→}n ((E)ABAcCD)n polymer were synthesized
