111727-15-2

Upstream product

• 97-30-3 methyl-alpha-D-glucopyranoside 
• 100-39-0 benzyl bromide 
• 7177-79-9 methyl 2,3-di-O-benzyl-4,6-O-benzylidene-α-D-glucopyranoside 
• 3162-96-7 methyl 4,6-O-benzylidene-α-D-glucopyranoside 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 17791-36-5 methyl 2,3-di-O-benzyl-α-D-glucopyranoside 

Downstream Products

• 111727-16-3 6-O-tert-butyldimethylsilyl-2,3-di-O-benzyl-4-O-(α-ethoxyethyl)-α-D-glucopyranoside 
• 89033-67-0 5-bromomethyl-thiazolidin-2-one 
• 495378-99-9 methyl 2,3-di-O-benzyl-6-O-tert-butyldimethylsilyl-4-O-p-methoxybenzyl-α-D-glucopyranoside 
• 776313-88-3 3-[2',3'-di-O-benzyl-4'-O-(4-nitrobenzoyl)-α-D-glucopyranosyl]-1-propene 
• 776313-90-7 4-nitro-benzoic acid (3aR,5R,6R,7R,7aS)-7-benzyloxy-5-hydroxymethyl-2-azidomethyl-hexahydro-furo[3,2-b]pyran-6-yl ester 
• 776313-89-4 4-nitro-benzoic acid (3aR,5R,6R,7R,7aS)-7-benzyloxy-5-hydroxymethyl-2-iodomethyl-hexahydro-furo[3,2-b]pyran-6-yl ester 
• 495379-01-6 methyl 2,3-di-O-benzyl-4-O-p-methoxybenzyl-6-O-triflyl-α-D-glucopyranoside 

Relevant academic research and scientific papers

Linearization of carbohydrate derived polycyclic frameworks

We report easy access to carbohydrate derived diverse tricyclic skeletons which could be beneficial for exploring polyfunctionalized chiral alicycles. The key reaction to assemble a sugar fused tricyclic core is intermolecular tandem esterification and 1,3-dipolar cycloaddition. The framework was elaborated using amide forming reactions, opening of isoxazolidine rings followed by N and O-acylations. The sequences provide distinct, spatially separated and encoded chemical entities that may pave the way to investigate cell functions.

Bicyclic carbohydrate-derived scaffolds for combinatorial libraries

A bicyclic scaffold derived from the natural monosaccharide d-glucose, and possessing several diversity sites, was linked to various resins through the primary (C-6) hydroxyl and decorated on the solid phase: the hydroxyl group at C-4 was functionalized a

CONTROLLED FORMATION OF DIPYRANOSIDE DERIVATIVES THROUGH C6 AND 04. PYRANOSIDIC HOMOLOGATION. VII

A procedure has been developed for pyranosidic homologation of methyl α-D-glucopyranoside via C4 and C6.Reaction of the aldehydo group of compound 2 with the Wittig-Bestmann reagent, Ph3P=CHCH(OEt)2, gave an E/Z mixture of acetals, 4, which cyclizes under