111752-63-7

Basic information

• Product Name: 2-Pentenoic acid, 4-(phenylmethoxy)-, ethyl ester, (E)-
• CAS NO: 111752-63-7
• Molecular Formula: C14H18O3
• Molecular Weight: 234.295
• Mol File: 111752-63-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-Pentenoic acid, 4-(phenylmethoxy)-, ethyl ester, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pentenoic acid, 4-(phenylmethoxy)-, ethyl ester, (E)-(111752-63-7)
• EPA Substance Registry System: 2-Pentenoic acid, 4-(phenylmethoxy)-, ethyl ester, (E)-(111752-63-7)

Safety Data

• Hazardous Substances Data: 111752-63-7(Hazardous Substances Data)

Upstream product

• 53346-05-7 2-(benzyloxy)propanal 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 100-39-0 benzyl bromide 
• 2040-44-0 ethyl 2-benzyloxypropionate 
• 16139-79-0 ethyl diphenylphosphonoacetate 

Downstream Products

• 111752-66-0 ethyl syn-4-(benzyloxy)-3-methylpentanoate 
• 111752-66-0 ethyl anti-4-(benzyloxy)-3-methylpentanoate 
• 143372-23-0 ethyl syn-3-(1-(benzyloxy)ethyl)-4-pentenoate 
• 143372-23-0 ethyl anti-3-(1-(benzyloxy)ethyl)-4-pentenoate 
• 143372-24-1 ethyl anti-3-(1-(benzyloxy)ethyl)-5-methyl-5-hexenoate 
• 143372-24-1 ethyl syn-3-(1-(benzyloxy)ethyl)-5-methyl-5-hexenoate 
• 111752-68-2 ethyl anti-4-(benzyloxy)-3-butylpentanoate 
• 111752-68-2 ethyl syn-4-(benzyloxy)-3-butylpentanoate 

Relevant articles and documents

Highly Selective Synthesis of Z-Unsaturated Esters by Using New Horner-Emmons Reagents, Ethyl (Diarylphosphono)acetates

New Horner-Emmons reagents, ethyl (diarylphosphono)acetates 1, were prepared from triethyl phosphonoacetate, PCl5 the corresponding phenols. The reaction of 1 with several kinds of aldehydes in the presence of Triton B or NaH in THF solvent revealed that these reagents are useful for the synthesis of Z-unsaturated esters. Among the reagents examined, ethyl(di-o-tolylphosphono)-, [bis(o-ethylphenyl)phosphonol-, and [bis(o-isopropylphenyl)phosphono]acetates (1k-m) were found to be the most effective, giving Z-unsaturated esters with 93-99% selectivity.

Highly E-selective solvent-free Horner-Wadsworth-Emmons reaction catalyzed by DBU

The solvent-free Horner-Wadsworth-Emmons reaction of triethyl phosphonoacetate with a variety of aldehydes was catalyzed by DBU in the presence of K2CO3 to give E-α,β-unsaturated esters highly selectively (99:1 for most of the reactions). The reaction with ketones gave trisubstituted olefins with good to high E-selectivity by DBU-Cs2CO3.

Diastereoselectivity of the conjugate addition of organocopper reagents to γ-alkoxy α,β-unsaturated carbonyl derivatives. Importance of the reagent type and the double-bond geometry

Systematic investigations of the diastereoselectivity of organocopper conjugate addition to γ-alkoxy trans enoates (3), cis enoates (4), and diesters (5) revealed that the selectivity highly depended on the substrate structure and the reagent type. The an