111795-60-9 Usage
Uses
Used in Pharmaceutical Industry:
1-(2-amino-3-hydroxy-4-(hydroxymethyl)cyclopentyl)-2(1H)-pyrimidinone is used as a potential therapeutic agent for the treatment of certain types of cancer. Its unique structure, including the cyclopentyl pyrimidinone ring system and the presence of an amino and hydroxy group, make it a promising candidate for further drug development. 1-(2-amino-3-hydroxy-4-(hydroxymethyl)cyclopentyl)-2(1H)-pyrimidinone has shown potential in inhibiting an enzyme involved in cancer progression, and its efficacy is currently being investigated in ongoing research.
Used in Cancer Research:
In the field of cancer research, 1-(2-amino-3-hydroxy-4-(hydroxymethyl)cyclopentyl)-2(1H)-pyrimidinone is used as a potential inhibitor of an enzyme that plays a role in the progression of certain types of cancer. This application is based on the compound's unique structural features, which allow it to target and potentially disrupt the enzyme's activity, thereby slowing down or preventing cancer progression.
Used in Drug Development:
1-(2-amino-3-hydroxy-4-(hydroxymethyl)cyclopentyl)-2(1H)-pyrimidinone is also used in the development of new drugs targeting cancer treatment. Its cyclopentyl pyrimidinone ring system and functional groups make it an attractive starting point for the design and synthesis of novel therapeutic agents. Researchers are exploring its potential in combination with other compounds or as a standalone treatment to improve the effectiveness of cancer therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 111795-60-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,1,7,9 and 5 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 111795-60:
(8*1)+(7*1)+(6*1)+(5*7)+(4*9)+(3*5)+(2*6)+(1*0)=119
119 % 10 = 9
So 111795-60-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H16N4O3/c11-7-1-2-14(10(17)13-7)6-3-5(4-15)9(16)8(6)12/h1-2,5-6,8-9,15-16H,3-4,12H2,(H2,11,13,17)/t5-,6-,8+,9-/m1/s1
111795-60-9Relevant academic research and scientific papers
Synthesis and Antiviral Evaluation of Carbocyclic Analogues of 2'-Azido- and 2'-Amino-2'-deoxycytidine
Lin, Tai-Shun,Zhang, Xiao-Hui,Wang, Zi-Hou,Prusoff, W.H.
, p. 484 - 486 (2007/10/02)
Carbocyclic analogues of 2'-azido- and 2'-amino-2'-deoxycytidine, compounds 8 and 9, were synthesized by an eight-step synthesis from (+/-)-(1α,2α,3β,5β)-3-amino-5-(hydroxymethyl)-1,2-cyclopentanediol (1), which was prepared from cyclopentadiene via an eight-step route.These compounds were tested in vitro against herpes simplex virus type 1 (HSV-1).The 2'-amino analogue was found to show moderate antiviral activity, with an ED50 of 50 μM.However, the 2'-azido analogue was not active at a concentration up to 400 μM.
