111822-93-6Relevant articles and documents
Novel Type of Potential Anticancer Agents Derived from Chrysophanol and Emodin. Some Structure-Activity Relationship Studies
Koyama, Masao,Kelly, T. Ross,Watanabe, Kyoichi A.
, p. 283 - 284 (1988)
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Derivatives of chryosphanol
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, (2008/06/13)
The present invention concerns compounds of the formula: STR1 wherein R1 hydrogen, a hydroxyl group or a methoxy group; R2 is hydrogen or a methyl group; R3 is hydrogen or a methyl group; Y is a halogen, a secondary amino group or a tertiary amino group; and Z is hydrogen or a halogen. The invention further concerns pharmaceutical compositions which comprises the above-identified compound or the acid salts thereof, and the use of the compound or compositions for treating a malignancy in a subject.