111828-01-4

Basic information

• Product Name: Acetonitrile, [(4-amino-5-phenyl-4H-1,2,4-triazol-3-yl)thio]-
• CAS NO: 111828-01-4
• Molecular Formula: C10H9N5S
• Molecular Weight: 231.281
• Mol File: 111828-01-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Acetonitrile, [(4-amino-5-phenyl-4H-1,2,4-triazol-3-yl)thio]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetonitrile, [(4-amino-5-phenyl-4H-1,2,4-triazol-3-yl)thio]-(111828-01-4)
• EPA Substance Registry System: Acetonitrile, [(4-amino-5-phenyl-4H-1,2,4-triazol-3-yl)thio]-(111828-01-4)

Safety Data

• Hazardous Substances Data: 111828-01-4(Hazardous Substances Data)

Upstream product

• 107-14-2 chloroacetonitrile 
• 22706-11-2 3-phenyl-4-amino-5-mercapto-1,2,4-triazole 
• 22706-11-2 4-amino-3-phenyl-1H-1,2,4-triazole-5(4H)-thione 
• 38539-87-6 potassium 3-benzoyldithiocarbazinate 

Downstream Products

• 114402-22-1 4H-4-amino-5-carboxymethylsulfanyl-3-phenyl-1,2,4-triazole 
• 113486-67-2 7H-6-Amino-3-phenyl-s-triazolo<3,4-b><1,3,4>thiadiazine 

Relevant articles and documents

1,2,4-Triazolo mercapto and aminonitriles as potent antifungal agents

A series of 3-mercapto-1,2,4-triazoles mono or disubstituted at 2-, 3- or 4-positions were synthesized and evaluated as antifungal agents. Many of these derivatives exhibit high activity against Candida albicans and Candida tropicalis.

STUDIES ON 4-AMINO-5-ARYL-1,2,4-TRIAZOLE-3-THIONES

4-Amino-5-aryl-1,2,4-triazole-3-thiones 1 react with phenacylbromide at room temperature to give 2, which could be converted to 3 on reflux. Treatment of 1 with chloroacetonitrile and potassium hydroxide in equimolar ratio and in excess yielded 4 and 6, r