111831-90-4

Basic information

• Product Name: 2-Bromo-3-(N-benzylmethylamino)prop-1-ene
• Synonyms: 2-Bromo-3-(N-benzylmethylamino)prop-1-ene;N-benzyl-2-bromo-N-methylprop-2-en-1-amine
• CAS NO: 111831-90-4
• Molecular Formula: C₁₁H₁₄BrN
• Molecular Weight: 240.13956
• Mol File: 111831-90-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Bromo-3-(N-benzylmethylamino)prop-1-ene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-3-(N-benzylmethylamino)prop-1-ene(111831-90-4)
• EPA Substance Registry System: 2-Bromo-3-(N-benzylmethylamino)prop-1-ene(111831-90-4)

Safety Data

• Hazardous Substances Data: 111831-90-4(Hazardous Substances Data)

Upstream product

• 103-67-3 benzyl-methyl-amine 
• 513-31-5 2-bromoallyl bromide 

Downstream Products

• 555-57-7 Pargyline 
• 100-39-0 benzyl bromide 

Relevant articles and documents

A Cascade Suzuki-Miyaura/Diels-Alder Protocol: Exploring the Bifunctional Utility of Vinyl Bpin

Cascade reactions are an important strategy in reaction design, allowing streamlining of chemical synthesis. Here we report a cascade Suzuki-Miyaura/Diels-Alder reaction, employing vinyl Bpin as a bifunctional reagent in two distinct roles: as an organoboron nucleo phile for cross-coupling and as a Diels-Alder dienophile. Merging these two reactions enables a rapid and operationally simple synthesis of functionalized carbocycles in good yield. The effect of the organoboron subtype on Diels-Alder regioselectivity was investigated and postsynthetic modifications were carried out on a model substrate. The potential for a complementary Heck/Diels-Alder process was also assessed.

SUBSTITUTED INTERNAL VINYL-BORONIC ACIDS AND BORONIC ACID DERIVATIVES

Disclosed herein are vinyl-bromides, vinyl-boronic acids and vinyl-boronic acid derivatives useful as synthetic intermediates for the preparation of therapeutic agents. Also disclosed are methods of synthesis of vinyl-bromides, vinyl-boronic acids and vin