111835-46-2

Upstream product

• 110-89-4 piperidine 
• 97651-04-2 6-methyl-4-phenyl-5-ethoxycarbonyl-3-cyano-3,4-dihydropyridine-2(1H)-thione 
• 97669-55-1 2,2'-Bis(3-cyano-4-phenyl-5-ethoxycarbonyl-6-methyl-1,4-dihydropyridyl) Disulfide 
• 7357-70-2 Cyanothioacetamide 
• 620-80-4 ethyl 2-benzylidene acetoacetate 

Downstream Products

• 111853-33-9 2-carbamoylmethylthio-6-methyl-4-phenyl-5-ethoxycarbonyl-3-cyano-1,4-dihydropyridine 
• 97651-04-2 6-methyl-4-phenyl-5-ethoxycarbonyl-3-cyano-3,4-dihydropyridine-2(1H)-thione 
• 111853-41-9 (3-cyano-5-ethoxycarbonyl-6-methyl-4-phenyl)pyridin-2-ylthioacetamide 
• 111853-43-1 3-amino-5-ethoxycarbonyl-6-methyl-4-phenylthieno[2,3-b]pyridine-2-carboxamide 
• 111853-37-3 3-amino-6-methyl-4-phenyl-5-ethoxycarbonyl-2-carbamoyl-4,7-dihydrothieno<2,3-b>pyridine 
• 111853-36-2 3-amino-6-methyl-4-phenyl-5-ethoxycarbonyl-2-cyano-4,7-dihydrothieno<2,3-b>pyridine 
• 111853-42-0 3-amino-6-methyl-4-phenyl-5-ethoxycarbonyl-2-cyanothieno<2,3-b>pyridine 
• 111853-40-8 2-cyanomethylthio-6-methyl-4-phenyl-5-ethoxycarbonyl-3-cyanopyridine 
• 111853-32-8 2-cyanomethylthio-6-methyl-4-phenyl-5-ethoxycarbonyl-3-cyano-1,4-dihydropyridine 
• 148148-03-2 2-methylthio-6-methyl-4-phenyl-5-ethoxycarbonyl-3-cyano-1,4-dihydropyridine 
• 97669-55-1 2,2'-Bis(3-cyano-4-phenyl-5-ethoxycarbonyl-6-methyl-1,4-dihydropyridyl) Disulfide 

Relevant academic research and scientific papers

SYNTHESIS OF 3-CYANO-4-ARYL-5-ETHOXYCARBONYL-6-METHYL-3,4-DIHYDROPYRIDINE-2-THIONES

The condensation of ethyl arylideneacetoacetate with cyanothioacetamide and of arylidenecyanothioacetamides with ethyl acetoacetate or of arylidenecyanothioacetamides with ethyl β-aminocrotonate gave 3-cyano-4-aryl-5-ethoxycarbonyl-6-methyl-3,4-dihydropyridine-2-thiones.PMR spectroscopy showed that the 3-cyano-4-aryl-3,4-dihydropyridine-2-thiones are formed as a mixture of cis and trans isomers.