111841-05-5

Usage

Uses

Used in Pharmaceutical Industry:
2-BROMO-1-(5-CHLORO-2-METHOXY-PHENYL)-ETHANONE is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new medicinal compounds.
Used in Organic Chemistry:
2-BROMO-1-(5-CHLORO-2-METHOXY-PHENYL)-ETHANONE serves as a versatile building block in organic chemistry, facilitating the creation of a range of organic compounds through its reactivity and structural features.
Used in Agrochemical Production:
2-BROMO-1-(5-CHLORO-2-METHOXY-PHENYL)-ETHANONE is utilized as a component in the production of agrochemicals, where its unique structure contributes to the effectiveness of these products.
Used in Specialty Chemicals:
2-BROMO-1-(5-CHLORO-2-METHOXY-PHENYL)-ETHANONE is also employed in the development of specialty chemicals, where its specific properties are leveraged to enhance the performance of these high-value products.
Used in Research and Development:
2-BROMO-1-(5-CHLORO-2-METHOXY-PHENYL)-ETHANONE is used as a research tool in the pharmaceutical industry for the exploration and development of new chemical entities, contributing to scientific advancements and innovation in drug discovery.

Upstream product

• 1450-74-4 5-chloro-2-hydroxyacetophenone 
• 6342-64-9 2-methoxy-5-chloroacetophenone 

Downstream Products

• 69316-10-5 3-(5-chloro-2-methoxyphenyl)-3-oxopropanenitrile 
• 847267-24-7 2-amino-1-(5-chloro-2-methoxy-phenyl)-ethanone hydrochloride 
• 1613144-16-3 N-(2-(5-chloro-2-methoxyphenyl)-2-oxoethyl)-N-(2-hydroxyphenyl)-4-methylbenzenesulfonamide 
• 1613144-28-7 benzo[d]oxazol-2-yl(5-chloro-2-methoxyphenyl)methanone 
• 374555-83-6 [4-(5-chloro-2-methoxyphenyl)-thiazol-2-yl]-[3-(imidazol-1-yl)phenyl]amine 
• 934340-41-7 C₁₆H₁₆ClNO₅ 
• 934340-38-2 C₁₅H₁₄ClNO₅ 
• 934340-26-8 C₁₃H₁₂ClNO₄ 

Relevant academic research and scientific papers

ROR-GAMMA INHIBITORS

The present invention relates to compounds of formula I and pharmaceutical compositions comprising compounds of formula I. Compounds of Formula I are useful in treatment of inflammatory, metabolic or autoimmune diseases which are mediated by RORy.

FLT3 RECEPTOR ANTAGONISTS

The invention pertains to novel FLT3receptor antagonists of general formula (1). The compounds are useful for the treatment or the prevention of pain disorders, cancer and autoimmune diseases.

A one-pot hypoiodite catalysed oxidative cycloetherification approach to benzoxazoles

A practical one-pot hypoiodite catalysed oxidative cyclization approach to synthesize α-ketobenzoxazole derivatives was successfully developed. This operationally simple protocol utilizes easily-accessible starting materials and has a broad substrate scope with excellent yields. This journal is the Partner Organisations 2014.

3-Substituted-(5-arylfuran-2-ylcarbonyl)guanidines as NHE-1 inhibitors

The C-3 substituents effect on NHE-1 inhibitory activity of (5-arylfuran-2-ylcarbonyl)guanidines, previously identified as potent NHE-1 inhibitors, was investigated. The introduction of amine or alkyl groups at the 3-position of the furan ring, next to the acylguanidine moiety, remarkably improves NHE-1 inhibitory potency. Especially the important finding is that 5-(2,5-dichloro)phenyl and 5-(2-methoxy-5-chloro)phenyl derivatives exhibit high NHE-1 inhibitory activities (IC50 0.02 μM) that match those of 3-unsubstituted derivatives.

COMPOUNDS, METHODS AND FORMULATIONS FOR THE ORAL DELIVERY OF A GLUCAGON LIKE PEPTIDE (GLP)-1 COMPOUND OR AN MELANOCORTIN 4 RECEPTOR (MC4) AGONIST PEPTIDE

The present invention relates to novel compounds, methods, and formulations useful for the oral delivery of a GLP-1 compound or an MC4 agonist peptide.

N-Vinylimidazoles and -triazoles and pharmaceutical compositions containing them

Described are N-vinylazoles of the general formula: (wherein R is hydrogen, hydroxy, halogen, C1-C5 alkoxy, C2-C5 alkenyloxy, optionally substituted benzyloxy, tetrahydropyranyl-oxy, difluoromethoxy, 2-(2,4-dich