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111853-35-1

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111853-35-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 111853-35-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,1,8,5 and 3 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 111853-35:
(8*1)+(7*1)+(6*1)+(5*8)+(4*5)+(3*3)+(2*3)+(1*5)=101
101 % 10 = 1
So 111853-35-1 is a valid CAS Registry Number.

111853-35-1Downstream Products

111853-35-1Relevant articles and documents

Synthesis of 6′-carbamoylmethylthio-5′-cyano-1′,4′- dihydro-3,4′-bipyridine-3′-carboxylic and 6′- carbamoylmethylthio-5′-cyano-1′,4′-dihydro-4, (...)

Krauze,Vilums,Cernova,Sile,Duburs

, p. 708 - 714 (2008/03/11)

The stability of solutions of esters of 6′-carbamoylmethylthio- 5′-cyano-2′-methyl-1′,4′-dihydro-4,4′-bipyridine- 3′-carboxylic acids was investigated by HPLC. The corresponding esters of 6′-carbamoylmethylthio-5′-cyano-4,4′-bipyridine-3′- carboxylic acids,esters of 8-cyano-5-methyl-3-oxo-7-(4-pyridyl)-2,3-dihydro-7H- thiazolo-[3,2-a]pyridine-6-carboxylic acids, methyl 3-amino-2-carbamoyl-6- methyl-4-(4-pyridyl)-4,7-dihydrothieno[2,3-b]pyridine-5-carboxylate, and methyl 3-amino-2-carbamoyl-6-methyl-4-(4-pyridyl)-thieno[2,3-b]pyridine-5-carboxylate were synthesized as standard compounds (typical impurities). Analysis by HPLC was realized under the conditions of reverse-phase chromatography. It was established that solutions of the investigated compounds (with mixtures of acetonitrile with phosphate buffer, having pH values of not less than 3 and not more than 5, as solvents) are stable for one month when the solutions are stored in a place protected against light. It is also necessary to use chromatographic systems in which the aqueous components have pH 3-5 during determination of the purity of the esters of 6′-carbamoylmethylthio-5′-cyano-2′- methyl-1′,4′-dihydro-4, 4′-bipyridine-3′-carboxylic acid by HPLC in order to separate the analyzed sorbates and their typical impurities more completely.

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