111897-21-3Relevant articles and documents
Synthesis and antihepatotoxicity of some Wuweizisu analogues
Wu,Chen,Chang,Chen,Lee
, p. 353 - 358 (1992)
A preparation of dimethyl 4,4'-dimethoxy-5,6,5',6'-dimethylenedioxybiphenyl-2,2'-dicarboxylate (VII) was readily achieved. It provided the advantages of specificity, simplicity, and efficiency in reactions. 6-Phenyl-3,9-dimethoxy-1,2-methylenedioxy-10,11-methylenedioxy-6,7- dihydro-5H-dibenz(c, e)azepin (X) was successfully synthesized from VII (DDB) and its liver-protective property proved to be more effective than DDB and silymarin in the in vitro test of carbon tetrachloride-induced damage of primary cultured rat hepatocytes.
Alkoxybiphenyl alpha, beta-unsaturated amide compound and preparing method and medical application thereof
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Paragraph 0123; 0125, (2018/10/19)
The invention relates to an alkoxybiphenyl alpha, beta-unsaturated amide compound and a preparing method and medical application thereof, and belongs to the fields of medicinal chemistry and pharmacotherapeutics. The invention provides application of the compound shown in the formula I or pharmaceutically acceptable salt thereof in preparing drugs for antioxidation related diseases, especially theapplication in preparing anti-inflammatory drugs or antioxidant drugs. (The formula is shown in the description.).
Bifendate derivatives, preparation method and its in the treatment of autoimmune diseases
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Paragraph 0274; 0275; 0276, (2016/10/09)
The invention belongs to the chemical medicine technical field, and especially relates to a bifendate derivative, a preparation method and an application of the bifendate derivative for treating autoimmune disease. A structure of the bifendate derivative