1372720-39-2Relevant academic research and scientific papers
Synthesis and biological evaluation of bifendate-chalcone hybrids as a new class of potential P-glycoprotein inhibitors
Gu, Xiaoke,Ren, Zhiguang,Tang, Xiaobo,Peng, Hui,Ma, Yuanfang,Lai, Yisheng,Peng, Sixun,Zhang, Yihua
, p. 2540 - 2548 (2012/05/31)
Overexpression of P-glycoprotein (P-gp) is one of the major problems to successful cancer chemotherapy. To find novel effective P-gp inhibitors, a series of bifendate-chalcone hybrids were synthesized and evaluated. Among them, the most active compound 8g
