111923-25-2Relevant academic research and scientific papers
THE SYNTHESIS OF THE ISOQUINOLINE ALKALOID CALYCOTOMINE VIA FUNCTIONALIZATION OF ENAMIDE DOUBLE BONDS
Lenz, George R.
, p. 721 - 730 (2007/10/02)
The novel alkaloid calycotomine, a 1-hydroxymethylenetetrahydroisoquinoline, has been synthesized from 1-methyl-3,4-dihydroisoquinoline via the 2-benzyloxycarbonyl enamide derivative.Oxidation of the enamide with osmium tetroxide results in bis-hydroxylat
