62210-73-5

Usage

Uses

Used in Organic Synthesis:
N-BENZYLOXYCARBONYLOXY-5-NORBORNENE-2,3-DICARBOXIMIDE, 99 is used as a reagent in organic synthesis for the preparation of various materials such as polymers, pharmaceuticals, and other organic compounds. Its unique structure and properties contribute to the synthesis of complex and valuable compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N-BENZYLOXYCARBONYLOXY-5-NORBORNENE-2,3-DICARBOXIMIDE, 99 is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its high purity and stability make it a reliable component in the development of new drugs and medications.
Used in Polymer Industry:
N-BENZYLOXYCARBONYLOXY-5-NORBORNENE-2,3-DICARBOXIMIDE, 99 is utilized in the polymer industry as a monomer or a building block for the synthesis of polymers with specific properties. Its unique structure allows for the creation of polymers with tailored characteristics for various applications.
Used in Research and Development:
In research and development, N-BENZYLOXYCARBONYLOXY-5-NORBORNENE-2,3-DICARBOXIMIDE, 99 serves as a valuable compound for exploring new chemical reactions and synthesis pathways. Its high purity and stability make it an ideal candidate for studying the properties and behavior of various organic compounds.

InChI:InChI=1/C17H15NO5/c19-15-13-11-6-7-12(8-11)14(13)16(20)18(15)23-17(21)22-9-10-4-2-1-3-5-10/h1-7,11-14H,8-9H2

Upstream product

• 21715-90-2 N-hydroxy-5-norbornene-2,3-dicarboximide 
• 1195164-50-1 N-hydroxy-5-norbomene-2,3-dicarboxylic acid imide 
• 501-53-1 benzyl chloroformate 
• 99502-89-3 Chlorameisensaeure-N-hydroxy-norborn-5-en-2,3-dicarboximidester 
• 100-51-6 benzyl alcohol 

Downstream Products

• 3160-59-6 N-benzyloxycarbonylamino-D-alloisoleucine 
• 129575-03-7 N-<1-glycyl>trans-3-<4-<1-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-<<(phenylmethoxy)carbonyl>amino>ethyl>phenoxy>-L-prolyl>-L-isoleucine methyl ester 
• 111923-14-9 5,6-Dimethoxy-1-methylene-3,4-dihydro-1H-isoquinoline-2-carboxylic acid benzyl ester 
• 64187-48-0 methyl (2S,4R)-1-benzyloxycarbonyl-4-hydroxypyrrolidine-2-carboxylate 
• 861143-79-5 (2R,3R)-2-((R)-1-Hydroxy-allyl)-3-[(S)-1-(2,4,6-triisopropyl-phenyl)-ethoxy]-pyrrolidine-1-carboxylic acid benzyl ester 
• 861143-77-3 (2R,3R)-2-((S)-1-Hydroxy-allyl)-3-[(S)-1-(2,4,6-triisopropyl-phenyl)-ethoxy]-pyrrolidine-1-carboxylic acid benzyl ester 
• 873326-66-0 (2S,3R,4R)-1-benzyl 2-methyl 3-(2-acetoxyethyl)-4-(tosyloxy)pyrrolidine-1,2-dicarboxylate 
• 88985-60-8 6'-N-(benzyloxycarbonyl)-3',4':5,6-di-O-cyclohexylidene-1,2',3-tri-N-tosylneamine 

Relevant academic research and scientific papers

Preparation method of plazomicin

The invention discloses a preparation method of plazomicin. According to the invention, 6'amino of sisomicin and Cbz-ONB make a nucleophilic substitution reaction under the action of selective coordination and chelation of zinc acetate to obtain a compound 2; all hydroxyl groups and other amino groups of the compound 2 are protected by using silanization reagent to generate a full silanization product; the full silanization product and N-t-butyloxycarboryl-4-amino-2(S)-hydroxybutyric acid make selective condensation and a silane protection group is removed to obtain a compound 4; other amino groups in the compound 4 are protected by a Boc protecting group to obtain a compound 5; and then reaction is performed on the compound 5 to obtain plazomicin. Compared with an original research route,the disclosed process has advantages of being short in synthesis steps, mild in experimental conditions, simple, easy to operate and thus is suitable for industrial production.

NOVEL ANTIBACTERIAL 3"-DERIVATIVES OF 4,6-DISUBSTITUTED 2,5-DIDEOXYSTREPTAMINE AMINOGLYCOSIDE ANTIBIOTICS

The present invention relates to novel aminoglycoside compounds having antimicrobial properties and being suitable, for example, as therapeutic agents for use in the treatment of mammalian disease and in particular to novel therapeutic agents suitable for use in the treatment of microbial infection in mammals. The present invention further relates to the use of pharmaceutical compositions comprising said agents in the treatment of medical conditions in mammals, in particular in the treatment of microbial infection. The agents and pharmaceutical compositions of the invention are of particular relevance in the treatment of diseases associated with antibiotic-resistant microbes. The invention further relates to compounds for use in the treatment of diseases whose treatment is made otherwise difficult due to antibiotic-class-related bacterial resistance and provides novel therapeutic agents suitable for use in the treatment of multidrug-resistant (MDR) infections.

RNA targeting compounds and methods for making and using same

Disclosed are RNA targeting compounds, methods for using the subject RNA targeting compounds to treat myotonic dystrophy and other diseases are also disclosed.

5-Norbornene-2,3-dicarboximido Carbonochloridate. A New Stable Reagent for the Introduction of Amino-Protecting Groups

The synthesis of activated carbonates, based on a new carbonochloridate derived from N-hydroxy-5-norbornene-2,3-dicarboximide, is reported.These activated carbonic esters are excellent reagents for the introduction of all currently used urethane protecting groups.