111964-18-2

Upstream product

• 195299-15-1 2-cyano-5-oxazolopyrrolidine 
• 111980-33-7 (-)-N-cyanomethylphenylglycinol 
• 56613-80-0 D-2-phenylglycinol 
• 111964-17-1 (3R,7aS)-5-Heptyl-3-phenyl-hexahydro-pyrrolo[2,1-b]oxazole-5-carbonitrile 

Downstream Products

• 112020-15-2 (R)-2-((2R,5S)-2-Butyl-5-heptyl-pyrrolidin-1-yl)-2-phenyl-ethanol 
• 111964-19-3 (R)-2-((2S,5S)-2-Butyl-5-heptyl-pyrrolidin-1-yl)-2-phenyl-ethanol 
• 95587-05-6 cis-2-heptyl-5-butylpyrrolidine 
• 116830-40-1 (S)-1-Benzenesulfonyl-2-heptyl-pyrrolidine 
• 105147-76-0 ((2R,5S)-2-Butyl-5-heptyl-pyrrolidin-1-yl)-phenyl-methanone 
• 119988-07-7 (+)-(S)-trans-2-heptyl-5-ethyl-1-benzylpyrrolidine 
• 120054-57-1 (2R,5S)-1-Benzyl-2-ethyl-5-heptyl-pyrrolidine 
• 119988-09-9 (S)-1-((2S,5S)-2-Ethyl-5-heptyl-pyrrolidin-1-yl)-3,3,3-trifluoro-2-methoxy-2-phenyl-propan-1-one 
• 105147-76-0 ((2S,5S)-2-Butyl-5-heptyl-pyrrolidin-1-yl)-phenyl-methanone 
• 111964-20-6 (S)-1-((2S,5S)-2-Butyl-5-heptyl-pyrrolidin-1-yl)-3,3,3-trifluoro-2-methoxy-2-phenyl-propan-1-one 
• 112020-16-3 cis-2-heptyl-5-butyl-1-benzyl pyrrolidine 
• 112020-14-1 (+)-(S)-trans-2-heptyl-5-butyl-1-benzyl pyrrolidine 
• 95587-14-7 (+)-(S)-trans-2-heptyl-5-butylpyrrolidine 
• 116830-30-9 (R)-2-((S)-2-Heptyl-pyrrolidin-1-yl)-2-phenyl-ethanol 

Relevant academic research and scientific papers

ASYMMETRIC SYNTHESIS XII: STEREOCONTROLLED ELECTROPHILIC-NUCLEOPHILIC α,α'-SUBSTITUTION OF THE PYRROLIDINE RING.

The synthesis of 2-cyano-5-oxazolopyrrolidine 3, a chiral pyrrolidine synthon, is described.Conditions were established that permitted sequential chemoselective reactions at the C-2 aminonitrile (electrophilic substitution) and at the C-5 aminoether (nucl

ASYMMETRIC SYNTHESIS XIII SYNTHESIS OF 2-ALKYLPYRROLIDINES : TOWARDS AZABICYCLIC SYSTEMS

The enantiospecific synthesis of a series of 2(S)-alkylpirrolidines from 2-cyano oxazolopyrrolidine synthon 1 is described.Two of the synthesised compunds represent key intermediates towards azabicyclic alkaloids.

ASYMMETRIC SYNTHESIS X : A CHIRAL PYRROLIDINE SYNTHON FOR A NEW APPROACH TO THE SYNTHESIS OF ALKALOIDS

The synthesis of chiral 2-cyano-5-oxazolopyrrolidine 3 is reported.The synthesis of the optically pure ant venom alkaloid, (+)-(S)-trans-2-heptyl-5-butyl-pyrrolidine 7, has been achieved from 3.