111964-18-2Relevant academic research and scientific papers
ASYMMETRIC SYNTHESIS XII: STEREOCONTROLLED ELECTROPHILIC-NUCLEOPHILIC α,α'-SUBSTITUTION OF THE PYRROLIDINE RING.
Arseniyadis, S.,Huang, P. Q.,Piveteau, D.,Husson, H.-P.
, p. 2457 - 2470 (2007/10/02)
The synthesis of 2-cyano-5-oxazolopyrrolidine 3, a chiral pyrrolidine synthon, is described.Conditions were established that permitted sequential chemoselective reactions at the C-2 aminonitrile (electrophilic substitution) and at the C-5 aminoether (nucl
ASYMMETRIC SYNTHESIS XIII SYNTHESIS OF 2-ALKYLPYRROLIDINES : TOWARDS AZABICYCLIC SYSTEMS
Arseniyadis , S.,Huang , P. Q.,Husson , H.-P.
, p. 631 - 634 (2007/10/02)
The enantiospecific synthesis of a series of 2(S)-alkylpirrolidines from 2-cyano oxazolopyrrolidine synthon 1 is described.Two of the synthesised compunds represent key intermediates towards azabicyclic alkaloids.
ASYMMETRIC SYNTHESIS X : A CHIRAL PYRROLIDINE SYNTHON FOR A NEW APPROACH TO THE SYNTHESIS OF ALKALOIDS
Huang, P. Q.,Arseniyadis, S.,Husson, H. -P.
, p. 547 - 550 (2007/10/02)
The synthesis of chiral 2-cyano-5-oxazolopyrrolidine 3 is reported.The synthesis of the optically pure ant venom alkaloid, (+)-(S)-trans-2-heptyl-5-butyl-pyrrolidine 7, has been achieved from 3.
