111971-29-0

Upstream product

• 696-61-7 4-tolylmagnesium chloride 
• 110-86-1 pyridine 

Downstream Products

• 111971-27-8 di-(p-bromomethylphenyl)-4,4' bipyridine-2,2' 
• 111971-31-4 4,4'-di(p-methylphenyl)-2,2'-bipyridine 
• 111971-30-3 2-bromo-4-(p-tolyl)pyridine 

Relevant academic research and scientific papers

Synthese de composes macrocycliques comportant deux fragments coordinants separes et differents, de type bipyridyl-2,2' et diphenyl-2,9 phenanthroline-1,10.

Macrocyclic compounds containing a 2,9-diphenyl-1,10-phenanthroline subunit and a peripheral 2,2'-bipyridine chelate have been synthesized.In compound 4, the links between both coordinating fragments are flexible enough to allow complete folding of the molecule during complexation whereas in 5, the complexing moieties are rigidly held apart and cannot bind to the same metallic center.

NOVEL SULFONYL DERIVATIVES

Sulfonyl derivatives represented by the following general formula (I): Q1-Q2-T1-Q3-SO2-QA and drugs containing the same (wherein Q1 is an optionally substituted, saturated or unsaturated, five- or six-membered cyclic hydrocarbon group, a five- or six-membered heterocyclic group, or the like; Q2 is a single band, oxygen, sulfur, C1-C6 alkylene or the like; QA is optionally substituted arylalkenyl, heteroarylalkenyl or the like; and T1 is carbonyl or the like). These compounds have potent FXa-inhibitory effects and promptly exert satisfactory and persistent antithrombotic effects through oral administration, thus being useful as anticoagulant agents little accompanied with side effects.