696-61-7

Usage

Chemical Properties

Dark colored solution

InChI:InChI=1/C7H7.ClH.Mg/c1-7-5-3-2-4-6-7;;/h3-6H,1H3;1H;/q;;+1/p-1/rC7H7ClMg/c1-6-2-4-7(9-8)5-3-6/h2-5H,1H3

Upstream product

• 106-43-4 para-chlorotoluene 
• 7439-95-4 magnesium 

Downstream Products

• 610-72-0 2,5-dimethylbenzoic acid 
• 68066-89-7 9-(4-methylbenzylidene)-9H-xanthene 
• 581-42-0 2.6-dimethylnaphthalene 
• 1498-79-9 9-(p-methylbenzyl)anthracene 
• 64199-11-7 diethyl-chloro-(4-methyl-benzyl)-silane 
• 104-09-6 4-methylphenylacetaldehyde 
• 2844-21-5 (E)-1-(4-methylphenyl)-2-(4-dimethylaminophenyl)-ethene 
• 15877-68-6 4-dimethylamino-2-phenyl-1-p-tolyl-butan-2-ol 
• 352-68-1 4-trifluoromethylthiotoluene 
• 58826-20-3 2ξ-(4-methoxy-4'-methyl-benzhydryl)-5r,6c-diphenyl-5,6-dihydro-imidazo[2,1-b]thiazol-3-one 
• 58826-22-5 2-(benzo[1,3]dioxol-5-yl-p-tolyl-methyl)-5r,6c-diphenyl-5,6-dihydro-imidazo[2,1-b]thiazol-3-one 
• 4423-10-3 4-(p-tolyl)pyridine 
• 92-52-4 biphenyl 
• 613-33-2 (4,4'-dimethyl-1,1'-biphenyl) 

Relevant academic research and scientific papers

Manganese-catalyzed oxidative homo-coupling of aryl Grignard chlorides

Manganese-catalyzed homo-coupling of aryl magnesium chlorides to give biphenyls was successfully achieved using manganese chloride as catalyst. A variety of aryl magnesium chlorides were efficiently converted into the corresponding symmetrical biaryls using 10 mol% MnCl2 as catalyst in the presence of a stoichiometric amount of 1,2-dichloroethane. Since the aryl chlorides, from which the Grignard reagents were prepared, are cheaper and more readily available that the corresponding bromides and iodides this procedure should become the method of choice for preparing symmetrical biaryls.

METHOD FOR PRODUCING BIPHENYL DERIVATIVE

Provided is a method for producing a biphenyl derivative, with an industrially high yield and excellent productivity, by use of a raw material which is low in cost and toxicity. More specifically, the method for producing the biphenyl derivative represented by general formula (1) is characterized in that a chlorine atom in a benzene derivative represented by general formula (2) reacts with magnesium metal to convert the benzene derivative into a Grignard reagent, and then the Grignard reagent is subjected to a coupling reaction in the presence of a catalyst and a dichloropropane: and (wherein A represents at least one selected from alkyl groups, alkoxy groups, alkoxymethyl groups, a vinyl group, phenyl groups and chlorine, and n represents an integer of 1 to 4).