111973-83-2Relevant academic research and scientific papers
Facile Synthesis of 4-alkylphenyl 4-(4-Nitrobenzoyloxy)Benzoate (DBXNO2) and its Cyano Analog (DBXCN)
Chiang, Long Y.
, p. 137 - 142 (2007/10/02)
Two series of unsymmetrical phenylbenzoate analogs of thermotropic liquid crystals, namely, 4-alkylphenyl 4(4-nitrobenzoyloxy) benzoate (DBXNO2) and its cyano analog (DBXCN) are synthesized by a new route from benzyloxybenzoic acid.The first ester linkage of these phenylbenzoates is made by a condensation reaction between benzyloxybenzoic acid and an alkylphenol in the presence of carbodiimide and a base to give compound 6.A benzyl deprotection reaction of 6 is carried out by catalytical hydrogenation to yield compound 7.The second ester connection is performed by a condensation reaction between 7 and p-cyano or p-nitrobenzoyl chloride.This reaction sequence leads to the final products, DBXNO2 or DBXCN, in an overall yield of 50percent or 37percent, respectively.
