111983-87-0Relevant academic research and scientific papers
A novel, rapid and green method of phosphorylation under ultrasound irradiation and catalyst free conditions
Bouzina, Abdeslem,Belhani, Billel,Aouf, Nour-Eddine,Berredjem, Malika
, p. 46272 - 46275 (2015/06/08)
The phosphorylation reaction of various N-acylamines, N-acylaminoesters N-acylaminoalcohols and N-acylsulfonamides with trimethylphosphite or triethylphosphite was effectively promoted under ultrasound irradiation, solvent and catalyst free conditions to produce the corresponding amidophosponate. This rapid method produced the products in short reaction times (5-15 min) and excellent yields (75-90%). This technique at a frequency of 40 kHz, strongly accelerates the process of formation of P-C bonds compared to the classic Arbuzov reaction. This journal is
Efficient method for the synthesis of α-amidophosphonates via the michaelis-arbuzov reaction
Lakoud, Samia Guezane,Berredjem, Malika,Aouf, Nour-Eddine
experimental part, p. 762 - 768 (2012/07/03)
A new series of modified β-amidophosphonates (or β- ketophosphonate) was synthesized by an efficient method, starting from aminoesters and chloroacetyl chloride. We have established that chloroacetyl chloride is a suitable reagent allowing the introduction a halogen moiety for the Arbuzov reaction. The α-amidophosphonates were prepared in two steps (acetylation, phosphorylation). Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file. Copyright
