1378030-82-0Relevant academic research and scientific papers
Efficient method for the synthesis of α-amidophosphonates via the michaelis-arbuzov reaction
Lakoud, Samia Guezane,Berredjem, Malika,Aouf, Nour-Eddine
, p. 762 - 768 (2012)
A new series of modified β-amidophosphonates (or β- ketophosphonate) was synthesized by an efficient method, starting from aminoesters and chloroacetyl chloride. We have established that chloroacetyl chloride is a suitable reagent allowing the introduction a halogen moiety for the Arbuzov reaction. The α-amidophosphonates were prepared in two steps (acetylation, phosphorylation). Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file. Copyright
