111992-93-9

Basic information

• Product Name: benzyl (4R)-4-((3R,7S,10S,13R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate
• Synonyms: benzyl (4R)-4-((3R,7S,10S,13R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate
• CAS NO: 111992-93-9
• Molecular Weight: 482.704
• Mol File: 111992-93-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: benzyl (4R)-4-((3R,7S,10S,13R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl (4R)-4-((3R,7S,10S,13R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate(111992-93-9)
• EPA Substance Registry System: benzyl (4R)-4-((3R,7S,10S,13R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate(111992-93-9)

Safety Data

• Hazardous Substances Data: 111992-93-9(Hazardous Substances Data)

Upstream product

• 128-13-2 ursodeoxycholic acid 
• 100-39-0 benzyl bromide 

Downstream Products

• 1486547-57-2 3-(benzyloxycarbonyloxy)-7-(methylthiomethoxy)ursodeoxycholic acid benzyl ester 
• 1486547-58-3 3-(benzyloxycarbonyloxy)-7-(chloromethoxy)ursodeoxycholic acid benzyl ester 
• 1486547-62-9 3-(methylthiomethoxy)-7-(benzyloxycarbonyloxy)ursodeoxycholic acid benzyl ester 
• 1486547-63-0 3-(chloromethoxy)-7-(benzyloxycarbonyloxy)ursodeoxycholic acid benzyl ester 
• 1486547-51-6 3-(bis(benzyloxy)phosphoryloxy)ursodeoxycholic acid benzyl ester 
• 1486547-55-0 3-(benzyloxycarbonyloxy)-7-(bis(benzyloxy)phosphoryloxy)ursodeoxycholic acid benzyl ester 
• 1486547-53-8 3-(benzyloxycarbonyloxy)ursodeoxycholic acid benzyl ester 
• 1486547-54-9 7-(benzyloxycarbonyloxy)ursodeoxycholic acid benzyl ester 

Relevant articles and documents

Superchiral Pd3L6 Coordination Complex and Its Reversible Structural Conversion into Pd3L3Cl6 Metallocycles

Large, non-symmetrical, inherently chiral bispyridyl ligand L derived from natural ursodeoxycholic bile acid was used for square-planar coordination of tetravalent PdII, yielding the cationic single enantiomer of superchiral coordination complex 1 Pd3L6 containing 60 well-defined chiral centers in its flower-like structure. Complex 1 can readily be transformed by addition of chloride into a smaller enantiomerically pure cyclic trimer 2 Pd3L3Cl6 containing 30 chiral centers. This transformation is reversible and can be restored by the addition of silver cations. Furthermore, a mixture of two constitutional isomers of trimer, 2 and 2′, and dimer, 3 and 3′, can be obtained directly from L by its coordination to trans- or cis-N-pyridyl-coordinating PdII. These intriguing, water-resistant, stable supramolecular assemblies have been thoroughly described by 1H DOSY NMR, mass spectrometry, circular dichroism, molecular modelling, and drift tube ion-mobility mass spectrometry.

COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF PARKINSON'S DISEASE

Methods of preventing or retarding or reversing or abolishing the onset of Parkinson's and other neurodegenerative diseases are discussed.

Glucuronidation of bile acids under flow conditions: Design of experiments and Koenigs-Knorr reaction optimization

An efficient method for the C3-glucuronidation of bile acids is developed under flow conditions. A modular mesoreactor assisted flow set-up was combined with statistical design of experiments to speed up the optimization of the Koenigs-Knorr re