1120330-75-7Relevant academic research and scientific papers
SALVINORIN DERIVATIVES AND USES THEREOF
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Page/Page column 46; 51-52, (2010/07/09)
The invention features salvinorin compositions that are selective for kappa opioid receptors; methods of treating mania by using a selective kappa receptor agonist; and methods of treating mood disorders, such as depressive disorders and manic disorders, using salvinorin compositions.
Modification of the furan ring of salvinorin A: Identification of a selective partial agonist at the kappa opioid receptor
Beguin, Cecile,Duncan, Katharine K.,Munro, Thomas A.,Ho, Douglas M.,Xu, Wei,Liu-Chen, Lee-Yuan,Carlezon Jr., William A.,Cohen, Bruce M.
experimental part, p. 1370 - 1380 (2009/08/08)
In an effort to find novel agents which selectively target the kappa opioid receptor (KOPR), we modified the furan ring of the highly potent and selective KOPR agonist salvinorin A. Introduction of small substituents at C-16 was well tolerated. 12-epi-Sal
