1121-46-6

Basic information

• Product Name: 2-FURAN-2-YL-ETHYLAMINE
• Synonyms: 2-(2-furyl)ethanamine(SALTDATA: FREE);2-FuranethanaMine;2-(Furan-2-yl)ethanamine;2-(2-furyl)ethylamine;2-(2-Aminoethyl)furan
• CAS NO: 1121-46-6
• Molecular Formula: C₆H₉NO
• Molecular Weight: 111.14176
• Mol File: 1121-46-6.mol
• Article Data: 20

Chemical Properties

• Melting Point: 204 °C
• Boiling Point: 162.47 °C at 760 mmHg
• Flash Point: 52.06 °C
• Appearance: /
• Density: 1.022g/cm³
• Vapor Pressure: 2.163mmHg at 25°C
• Refractive Index: 1.494
• PKA: 9.59±0.10(Predicted)
• CAS DataBase Reference: 2-FURAN-2-YL-ETHYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-FURAN-2-YL-ETHYLAMINE(1121-46-6)
• EPA Substance Registry System: 2-FURAN-2-YL-ETHYLAMINE(1121-46-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 1121-46-6(Hazardous Substances Data)

Usage

General Description

2-FURAN-2-YL-ETHYLAMINE, also known as 2-(2-Amin-ethyl)-furan, is an organic compound that belongs to the class of amines. It is a colorless to pale yellow liquid that has a strong, pungent odor. This chemical is commonly used in the manufacturing of pharmaceuticals and as a building block in organic synthesis. It is also used as a flavoring agent in the food industry. 2-FURAN-2-YL-ETHYLAMINE is considered to be potentially hazardous and may cause irritation to the skin, eyes, and respiratory system. Proper handling and safety precautions should be taken when working with this chemical.

InChI:InChI=1/C6H9NO/c7-4-3-6-2-1-5-8-6/h1-2,5H,3-4,7H2

Upstream product

• 699-18-3 2-(2-nitrovinyl)furan 
• 98-01-1 furfural 
• 75-52-5 nitromethane 
• 86423-56-5 Diethyl N-[β-(furan-2-yl)-vinyl]-phosphoramidate 
• 699-18-3 2-[(E)-2-nitroethenyl]furan 
• 86423-57-6 diethyl N-[2-(furan-2-yl)-ethyl]-phosphoramidate 
• 855688-88-9 (2-[2]furyl-ethyl)-carbamic acid benzyl ester 
• 52239-33-5 1-(furan-2-yl)-2-nitroethanol 
• 98334-58-8 3-[2]furyl-propionic acid hydrazide 
• 10031-90-0 ethyl 3-(furan-2-yl)propanoate 

Downstream Products

• 102475-07-0 (3-benzyloxy-4-methoxy-benzylidene)-(2-[2]furyl-ethyl)-amine 
• 98277-97-5 2-(tetrahydrofuran-2-yl)ethylamine 
• 5669-02-3 N-<2-(2-furyl)ethyl>benzamide 
• 3410-08-0 1--2-dimethylamino-ethan-methojodid 
• 344882-03-7 2-(2-Furan-2-yl-ethylamino)-4-(methyl-phenyl-amino)-5-sulfamoyl-benzenesulfonic acid phenyl ester 
• 859163-22-7 N-(2-furan-2-yl-ethyl)-N-4-nitrobenzenesulfonamide 
• 95469-28-6 4-phenyl-6,7-dihydrofuro<3,2-c>pyridine 
• 129823-18-3 5-<(3,4-dichlorophenyl)acetyl>-4,5,6,7-tetrahydrofuro<3,2-c>pyridine-4-methanol 

Relevant articles and documents

Design, synthesis, and biological evaluation of new inhibitors of the endocannabinoid uptake: Comparison with effects on fatty acid amidohydrolase

A new series of arachidonic acid derivatives were synthesized and evaluated as inhibitors of the endocannabinoid uptake. Most of them are able to inhibit anandamide uptake with IC50 values in the low micromolar range (IC50 = 0.8-24 μM). ln general, the compounds had only weak effects upon CB1, CB2, and VR1 receptors (Ki > 1000-10000 nM). In addition, there was no obvious relationship between the abilities of the compounds to affect anandamide uptake and to inhibit anandamide metabolism by fatty acid amidohydrolase (FAAH; IC50 = 30-113 μM). This indicates that the compounds do not exert their effects secondarily to FAAH inhibition. It is hoped that these compounds, particularly the most potent in this series (compound 5, UCM707, with IC50 values for anandamide uptake and FAAH of 0.8 and 30 μM, respectively), will provide useful tools for the elucidation of the role of the anandamide transporter system in vivo.

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Unified Synthesis of Polycyclic Alkaloids by Complementary Carbonyl Activation**

A complementary dual carbonyl activation strategy for the synthesis of polycyclic alkaloids has been developed. Successful applications include the synthesis of tetracyclic alkaloids harmalanine and harmalacinine, pentacyclic indoloquinolizidine alkaloid nortetoyobyrine, and octacyclic β-carboline alkaloid peganumine A. The latter synthesis features a protecting-group-free assembly and an asymmetric disulfonimide-catalyzed cyclization. Furthermore, formal syntheses of hirsutine, deplancheine, 10-desbromoarborescidine A, and oxindole alkaloids rhynchophylline and isorhynchophylline have been achieved. Finally, a concise synthesis of berberine alkaloid ilicifoline B was completed.

LIVER X RECEPTORS (LXR) MODULATORS

The present invention relates to sulfonamide-, sulfinamide- or sulfonimidamide containing compounds which bind to the liver X receptor (LXRa and/or LXR?) and act preferably as inverse agonists of LXR.

ORGANIC METAL COMPOUND, ORGANIC LIGHT-EMITTING DEVICES EMPLOYING THE SAME

Organic metal compounds, and organic light-emitting devices employing the same are provided. The organic metal compound has a chemical structure represented by formula (I): wherein each R1 is independent and can be hydrogen, C1-12 al