112109-69-0

Basic information

• Product Name: 1-PIVALOYL-2,3,5-TRIMETHYLHYDROQUINONE
• Synonyms: 1-PIVALOYL-2,3,5-TRIMETHYLHYDROQUINONE;2,2-DiMethyl-propanoic Acid 4-Hydroxy-2,3,5-triMethylphenyl Ester
• CAS NO: 112109-69-0
• Molecular Formula: C₁₄H₂₀O₃
• Molecular Weight: 237.31474
• Product Categories: Aromatics Compounds;Aromatics
• Mol File: 112109-69-0.mol
• Article Data: 7

Chemical Properties

• Melting Point: 120-122°C
• Boiling Point: 332.3±30.0 °C(Predicted)
• Appearance: /
• Density: 1.055±0.06 g/cm3(Predicted)
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 10.39±0.30(Predicted)
• CAS DataBase Reference: 1-PIVALOYL-2,3,5-TRIMETHYLHYDROQUINONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-PIVALOYL-2,3,5-TRIMETHYLHYDROQUINONE(112109-69-0)
• EPA Substance Registry System: 1-PIVALOYL-2,3,5-TRIMETHYLHYDROQUINONE(112109-69-0)

Safety Data

• Hazardous Substances Data: 112109-69-0(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Uses

1-Pivaloyl-2,3,5-trimethylhydroquinone (cas# 112109-69-0) is a compound useful in organic synthesis.

Upstream product

• 700-13-0 Trimethylhydroquinone 
• 3282-30-2 pivaloyl chloride 

Downstream Products

• 223133-14-0 2-acetoxymethyl-5-(4-acetoxy-2,3,5-trimethylphenoxy)-3-methyl-3H-imidazo[4,5-b]pyridine 
• 223133-15-1 5-(4-Acetoxy-2,3,5-trimethylphenoxy)-2-hydroxymethyl-3-methyl-3H-imidazo[4,5-b]pyridine 
• 223133-13-9 2-hydroxymethyl-5-(4-hydroxy-2,3,5-trimethylphenoxy)-3-methyl-3H-imidazo[4,5-b]pyridine 
• 223133-11-7 6-(4-methoxymethoxy-2,3,5-trimethylphenoxy)-2-methylamino-3-nitropyridine 
• 223133-17-3 t-butyl N-[2-amino-5-(4-methoxymethoxy-2,3,5-trimethylphenoxy)phenyl]-N-methylcarbamate 
• 1629281-17-9 C₁₅H₂₂O₃ 
• 1629168-06-4 C₂₉H₄₈O₄ 
• 1629168-03-1 1-(2-hydroxy-5-methoxy-3,4,6-trimethylphenyl)ethanone 
• 186537-56-4 (2RS,4R,8R)-α-tocopherol 
• 130422-86-5 4-methoxy-2,3,5-trimethylphenol 
• 223133-10-6 4-methoxymethoxy-2,3,5-trimethylphenol 
• 112109-67-8 5-<4-<(tert-Butyldimethylsilyl)oxy>-2,3,5-trimethylphenoxy>-2,2-dimethylpentanoic acid 
• 112109-73-6 9-(4-Hydroxy-2,3,5-trimethyl-phenoxy)-2,2-dimethyl-nonanoic acid 
• 112109-68-9 3-<4-<(tert-Butyldimethylsilyl)oxy>-2,3,5-trimethylphenoxy>propyl bromide 

Relevant articles and documents

BIOISPIRED PROTEASOME ACTIVATORS WITH ANTIAGEING ACTIVITY

The present invention relates to novel bio-inspired hybrid compounds of formula I which act as proteasome activators and exhibit anti-ageing activity, as well as methods for their synthesis. These hybrid compounds combine the structural features of hydroxytyrosol and the natural antioxidant vitamin E or its bioisosteres in one molecular scaffold. The compounds of formula I, which include structural proteasome activators (activation by stereochemical interaction), can be used in the production of anti-ageing products, such as cosmetic preparations. Additionally, they can be used in conditions and diseases where the proteasome is down-regulated, as well as proteasome-activation control compounds.

A straightforward hetero-diels-alder approach to (2-ambo,4′R, 8′R)-α/β/γ/δ-4-thiatocopherol

A simple and original inverse electron demand hetero-Diels-Alder reaction has been successfully applied to the synthesis of (2-ambo,4′R,8′R)- α/β/γ/δ-4-thiatocopherol. Commercially available methyl hydroquinones and. (2E,7R,11R)-(+)-phytol were exploited for the preparation of the ortho-thioquinones, acting as electron-poor dienes, and of the proper 1,3-diene used as dienophile, respectively. The benzoxathiine cycloadducts, with the required tocopherol-like skeleton, were obtained with complete control, of regio and chemoselectivity. The antioxidant activity of 4-thiatocopherols was measured and rationalized in comparison with that of the corresponding natural components of Vitamin E.

Synthesis of 4-alkoxyaryl β-D-glucopyranosides and their inhibitory effects on histamine release from rat peritoneal mast cells induced by concanavalin A

The inhibitory effects of newly synthesized 4-alkoxyaryl β-D- glucopyranosides on histamine release from rat peritoneal mast cells induced by concanavalin A were examined. A plot of hydrophobicity (k') against inhibitory activity of the compounds showed a distinct maximum, and 4- decyloxy-2,3,6-trimethylphenyl β-D-glucopyranoside was the most potent inhibitor among the tested compounds.