112117-81-4

Basic information

• Product Name: 4-[bis-(2-chloro-ethyl)-amino]-L-phenylalanine ethyl ester; hydrochloride
• Synonyms: 4-[bis-(2-chloro-ethyl)-amino]-L-phenylalanine ethyl ester; hydrochloride
• CAS NO: 112117-81-4
• Molecular Weight: 369.719
• Mol File: 112117-81-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[bis-(2-chloro-ethyl)-amino]-L-phenylalanine ethyl ester; hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[bis-(2-chloro-ethyl)-amino]-L-phenylalanine ethyl ester; hydrochloride(112117-81-4)
• EPA Substance Registry System: 4-[bis-(2-chloro-ethyl)-amino]-L-phenylalanine ethyl ester; hydrochloride(112117-81-4)

Safety Data

• Hazardous Substances Data: 112117-81-4(Hazardous Substances Data)

Upstream product

• 792864-20-1 N-phthalimido-4-(bis-2-chloroethyl)amino-L-phenylalanine ethyl ester 

Downstream Products

• 13331-67-4 N-Formyl-L-phenylalanyl-melphalan-ethylester 
• 116890-08-5 N-Succinamino-p--L-phenylalanin-ethylester 
• 95819-94-6 Phe-Mel-OEt 
• 95403-25-1 Leu-Mel-OEt 
• 95462-39-8 Val-Mel-OEt 
• 103773-22-4 D-Ala-Mel-OEt 
• 103773-22-4 N-Alanyl-3-(4--phenyl)-α-alanin-ethylester 
• 32132-72-2 3-{4-[Bis-(2-chloro-ethyl)-amino]-phenyl}-2-(2-bromo-acetylamino)-propionic acid ethyl ester 
• 13057-61-9 N-Formyl-p--L-phenylalanin-ethylester 
• 14504-87-1 Ac-p-NO2-D-Phe-Mel-OEt 
• 14504-87-1 Ac-p-NO2-L-Phe-Mel-OEt 
• 116607-01-3 Z-L-Phe-Mel-OEt 
• 13555-25-4 Ac-L-Phe-Mel-OEt 
• 125596-66-9 Z-L-Val-Mel-OEt 

Relevant articles and documents

Processes for preparing pharmaceutical grade melphalans from industrial grade reactants

A four stage inexpensive method of preparing pharmaceutical grade Melphalans of Melphalan 2-HCl, Melphalan HCl and Melphalan by: reacting N- phthaloyl-4-[bis(2-hydroxyethyl)amino]-phenylalanine ethyl ester with phosphorous oxychloride, reacting the chlorinated product with HCl and alkali hydroxide and purifying, and lyophilizing to obtain Melphalans.