1121586-23-9

Upstream product

• 62554-90-9 4-bromo-2,6-dinitroaniline 
• 606-22-4 2,6-dinitroaniline 

Downstream Products

• 1401450-86-9 N-cyclopropyl-4-{6-(3-fluoro-4-methoxybenzoyl)-4-[(3,3,3-trifluoropropyl)amino]-1H-benzimidazol-1-yl}-2-methylbenzamide 
• 1401450-87-0 4-{6-(3-fluoro-4-methoxybenzoyl)-4-[(3,3,3-trifluoropropyl)amino]-1H-benzimidazol-1-yl}-2-methylbenzoic acid 
• 1401450-89-2 1-[4-(methoxycarbonyl)-3-methylphenyl]-4-[(3,3,3-trifluoropropyl)amino]-1H-benzimidazole-6-carboxylic acid 
• 1401450-88-1 methyl 4-{6-(3-fluoro-4-methoxybenzoyl)-4-[(3,3,3-trifluoropropyl)amino]-1H-benzimidazol-1-yl}-2-methylbenzoate 
• 1401450-90-5 N-cyclopropyl-4-{6-[(3-fluoro-4-methoxyphenyl)(hydroxy)methyl]-4-[(3,3,3-trifluoropropyl)amino]-1H-benzimidazol-1-yl}-2-methylbenzamide 
• 1401450-91-6 N-cyclopropyl-4-{6-[(1RS)-1-(3-fluoro-4-methoxyphenyl)-1-hydroxyethyl]-4-[(3,3,3-trifluoropropyl)amino]-1H-benzimidazol-1-yl}-2-methylbenzamide 
• 1401450-92-7 N-cyclopropyl-4-{6-[(1RS)-1-(3-fluoro-4-methoxyphenyl)-1-hydroxyethyl]-4-[(3,3,3-trifluoropropyl)amino]-1H-benzimidazol-1-yl}-2-(hydroxymethyl)benzamide 
• 1401450-93-8 N-cyclopropyl-4-{6-[1-(3-fluoro-4-methoxyphenyl)vinyl]-4-[(3,3,3-trifluoropropyl)amino]-1H-benzimidazol-1-yl}-2-methylbenzamide 
• 1401450-94-9 N-cyclopropyl-4-{6-[(1RS)-1-(3-fluoro-4-methoxyphenyl)ethyl]-4-[(3,3,3-trifluoropropyl)amino]-1H-benzimidazol-1-yl}-2-methylbenzamide 
• 1401450-95-0 N-cyclopropyl-4-{6-(3-fluoro-4-methoxybenzyl)-4-[(3,3,3-trifluoropropyl)amino]-1H-benzimidazol-1-yl}-2-methylbenzamide 
• 1401449-61-3 4-(4-amino-6-bromo-1H-benzimidazol-1-yl)-N-cyclopropyl-2-methylbenzamide 
• 1401449-62-4 4-{6-bromo-4-[(3,3,3-trifluoropropyl)amino]-1H-benzimidazol-1-yl}-N-cyclopropyl-2-methylbenzamide 
• 1401449-66-8 N-cyclopropyl-2-methyl-4-{6-(pyridin-4-yl)-4-[(3,3,3-trifluoropropyl)amino]-1H-benzimidazol-1-yl}benzamide 
• 1401449-67-9 N-cyclopropyl-4-{6-[(5-fluoro-2-methylphenyl)amino]-4-[(3,3,3-trifluoropropyl)amino]-1H-benzimidazol-1-yl}-2-methylbenzamide 

Relevant academic research and scientific papers

SUBSTITUTED BENZIMIDAZOLES

The present invention relates to substituted benzimidazole compounds of general formula (I) in which R3, R5 and A are as defined in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.