1121613-46-4 Usage
Chemical structure
Piperazine derivative with a fluorine atom and a methoxy group attached to a phenyl ring
Potential applications
Medicinal chemistry and pharmaceutical research
Psychoactive properties
Investigated for potential as psychoactive drugs, anxiolytics, and antipsychotics
Pharmacological properties
Presence of fluorine and methoxy group may impart specific properties
Importance
Potentially important compound for further study in drug development
Check Digit Verification of cas no
The CAS Registry Mumber 1121613-46-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,2,1,6,1 and 3 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1121613-46:
(9*1)+(8*1)+(7*2)+(6*1)+(5*6)+(4*1)+(3*3)+(2*4)+(1*6)=94
94 % 10 = 4
So 1121613-46-4 is a valid CAS Registry Number.
1121613-46-4Relevant academic research and scientific papers
Identification of novel GLUT inhibitors
Siebeneicher, Holger,Bauser, Marcus,Buchmann, Bernd,Heisler, Iring,Müller, Thomas,Neuhaus, Roland,Rehwinkel, Hartmut,Telser, Joachim,Zorn, Ludwig
, p. 1732 - 1737 (2016/07/27)
The compound class of 1H-pyrazolo[3,4-d]pyrimidines was identified using HTS as very potent inhibitors of facilitated glucose transporter 1 (GLUT1). Extensive structure–activity relationship studies (SAR) of each ring system of the molecular framework was established revealing essential structural motives (i.e., ortho-methoxy substituted benzene, piperazine and pyrimidine). The selectivity against GLUT2 was excellent and initial in vitro and in vivo pharmacokinetic (PK) studies are encouraging.
