1121931-07-4Relevant academic research and scientific papers
Synthesis and pharmacological evaluation of indole-based sigma receptor ligands
Mésangeau, Christophe,Amata, Emanuele,Alsharif, Walid,Seminerio, Michael J.,Robson, Matthew J.,Matsumoto, Rae R.,Poupaert, Jacques H.,McCurdy, Christopher R.
, p. 5154 - 5161 (2011)
A series of novel indole-based analogs were prepared and their affinities for sigma receptors were determined using in vitro radioligand binding assays. The results of this study identified several compounds with nanomolar sigma-2 affinity and significant
HIGHLY SELECTIVE SIGMA RECEPTOR LIGANDS
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Page/Page column 25; 42, (2009/04/25)
A compound useful for treating subjects in need of therapy involving sigma receptors or for alleviation of affects resulting from drug abuse having the general formula ( I ) in which R1 can be a radical of an optionally substituted C-4 to C-7 N
